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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CASP10 / Caspase 10 Antibody (clone 1D8) LS‑C196820
Caspase 10 antibody LS-C196820 is an unconjugated mouse monoclonal antibody to human Caspase 10 (CASP10). Validated for ELISA.
Catalog
Size
Price
LS-C196820-100
100 µg
Unavailable

Popular CASP10 / Caspase 10 Products

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Immunohistochemical analysis of Caspase 10 staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Product Description

Caspase 10 antibody LS-C196820 is an unconjugated mouse monoclonal antibody to human Caspase 10 (CASP10). Validated for ELISA.
About CASP10 / Caspase 10
CASP10 / Caspase 10 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Q92851 NM_001230 NP_001221.2

CASP10 Antibody, ALPS2 Antibody, Caspase-10 Antibody, Caspase 10 Antibody, CASP-10 Antibody, FADD-like ICE2 Antibody, FLICE2 Antibody, MCH4 Antibody, ICE-like apoptotic protease 4 Antibody, Apoptotic protease Mch-4 Antibody


Specifications

Target
Human CASP10 / Caspase 10
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal [1D8]
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Applications
  • ELISA
Immunogen
CASP10 (NP_116756, aa1-110 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human CASP10 / Caspase 10
Usage
Sandwich ELISA: Recombinant protein.
Presentation
PBS, pH 7.4
Storage
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged CASP10 is approximately 0.03 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged CASP10 is approximately 0.03 ng/ml as a capture antibody.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged CASP10 is approximately 0.03 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged CASP10 is approximately 0.03 ng/ml as a capture antibody.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged CASP10 is approximately 0.03 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged CASP10 is approximately 0.03 ng/ml as a capture antibody.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged CASP10 is approximately 0.03 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged CASP10 is approximately 0.03 ng/ml as a capture antibody.


Requested From: 
Date Requested: 6/23/2018

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