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Anti-CASP1 / Caspase 1 Antibody IHC-plus™ LS-B3394

Note: This antibody replaces LS-C50656

Ordering

Wt. Vol. Conc. Price
- 250 µl - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CASP1 / Caspase 1 Antibodies

Anti-CASP1 / Caspase 1 Antibody (aa371-390, clone 14F468) IHC-plus™ LS-B112
Mouse Monoclonal [clone 14F468] (IgG1,k) to Human CASP1 / Caspase 1
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-CASP1 / Caspase 1 Antibody LS-C48131
Rabbit Polyclonal to Human CASP1 / Caspase 1
Human, Mouse, Rat
Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human CASP1 / Caspase 1
Human
IHC - Paraffin
Unconjugated

Details

Human CASP1 / Caspase 1
Rabbit
Human (tested or 100% immunogen sequence identity)
Mouse, Rat, Bovine, Dog, Pig (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

IHC - Paraffin (1:50)

Specificity and Use

CASP1 / Caspase 1 antibody was raised against a synthetic peptide from the second quarter of human Caspase 1 protein.
Immunohistochemistry: LS-B3394 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3394 was determined to be 1:50.

Packaging

10 mM PBS, pH 7.4, BSA, sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About CASP1 / Caspase 1

P29466 NM_001223 NP_001214.1

CASP1 Antibody, Caspase-1 Antibody, CASP-1 Antibody, CASP1 nirs variant 1 Antibody, Caspase 1 Antibody, ICE Antibody, ICE-like protease Antibody, IL-1 beta-converting enzyme Antibody, IL-1BC Antibody, IL1BC Antibody, IL1BCE Antibody, p45 Antibody, IL1B-convertase Antibody, Interleukin-1 beta convertase Antibody

CASP1 / Caspase 1 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.

Immunohistochemistry

Immunohistochemistry
Anti-Caspase 1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3394 dilution 1:50.
 

Requested From: United States
Date Requested: 12/4/2016

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