CARD9

caspase recruitment domain family, member 9

Adapter protein that plays a key role in innate immune response to a number of intracellular pathogens, such as C.albicans and L.monocytogenes. Is at the crossroads of ITAM-tyrosine kinase and the Toll-like receptors (TLR) and NOD2 signaling pathways. Probably controls various innate immune response pathways depending on the intracellular pathogen. In response to L.monocytogenes infection, acts by connecting NOD2 recognition of peptidoglycan to downstream activation of MAP kinases (MAPK) without activating NF-kappa-B. Also involved in activation of myeloid cells via classical ITAM-associated receptors and TLR: required for TLR-mediated activation of MAPK, while it is not required for TLR-induced activation of NF-kappa-B (By similarity). Controls CLEC7A (dectin-1)-mediated myeloid cell activation induced by the yeast cell wall component zymosan, leading to cytokine production and innate anti-fungal immunity: acts by regulating BCL10-MALT1-mediated NF-kappa-B activation pathway. Activates NF-kappa-B via BCL10. In response to the hyphal form of C.albicans, mediates CLEC6A (dectin-2)-induced I-kappa-B kinase ubiquitination, leading to NF-kappa-B activation via interaction with BCL10. In response to fungal infection, may be required for the development and subsequent differentiation of interleukin 17-producing T helper (TH-17) cells.

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Products

Antibodies (31)

Proteins (10)

Type

Over-Expression Lysate (4)

Primary (31)

Recombinant (6)

Target

CARD9 (41)

Reactivity

Human (22)

Mouse (9)

Rat (1)

Gibbon (3)

Horse (3)

Monkey (3)

Application

IHC (4)

IHC-P (2)

WB (29)

ELISA (6)

ICC (3)

IF (2)

IP (2)

Peptide-ELISA (1)

Host

rabbit (29)

mouse (2)

Product Group

IHCPlus (1)

Isotype

IgG (9)

IgG1 (1)

Clonality

monoclonal mc (1)

polyclonal pc (30)

Clone

OTI3F8 (1)

Format

APC (2)

APC Conjugated (2)

Biotin Conjugated (3)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (14)

Epitope

aa26-283 (8)

aa274-530 (8)

aa467-516 (4)

N-Terminus (1)

aa237-536 (1)

aa521-536 (1)

Publications

No (41)

Tag

GST (1)

GST, N-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (6)

Species

Human (7)

Mouse (1)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (4)

Wheat Germ Extract (2)

Purification

Purified (1)

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IHC-plus™ CARD9 Antibody LS-B473

(4.0) Rating

Antibody:

CARD9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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CARD9 Antibody (N-Terminus) LS-C46821

Antibody:

CARD9 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$379

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CARD9 Antibody (aa274-530) LS-C293224

Antibody:

CARD9 Rabbit anti-Mouse Polyclonal (aa274-530) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

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CARD9 Antibody (aa274-530, HRP) LS-C714692

Antibody:

CARD9 Rabbit anti-Mouse Polyclonal (aa274-530) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$355; 200 µl/$417; 500 µl/$635; 1 ml/$792; 2 ml/$1,030; 5 ml/$1,803

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CARD9 Antibody (aa274-530, Biotin) LS-C689561

Antibody:

CARD9 Rabbit anti-Mouse Polyclonal (aa274-530) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$333; 200 µl/$385; 500 µl/$559; 1 ml/$671; 2 ml/$907; 5 ml/$1,525

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CARD9 Antibody (aa274-530, FITC) LS-C696692

Antibody:

CARD9 Rabbit anti-Mouse Polyclonal (aa274-530) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$366; 200 µl/$432; 500 µl/$683; 1 ml/$842; 2 ml/$1,088; 5 ml/$1,941

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CARD9 Antibody (aa274-530, APC, Cy7) LS-C737612

Antibody:

CARD9 Rabbit anti-Mouse Polyclonal (aa274-530) (APC, Cy7) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$543; 200 µl/$732; 500 µl/$1,268; 1 ml/$1,585; 2 ml/$2,219; 5 ml/$4,159

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CARD9 Antibody (aa274-530, PE) LS-C728762

Antibody:

CARD9 Rabbit anti-Mouse Polyclonal (aa274-530) (PE) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773

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CARD9 Antibody (aa274-530, APC) LS-C719792

Antibody:

CARD9 Rabbit anti-Mouse Polyclonal (aa274-530) (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773

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CARD9 Antibody (aa274-530, Cy3) LS-C705678

Antibody:

CARD9 Rabbit anti-Mouse Polyclonal (aa274-530) (Cy3) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773

• Unconjugated
• HRP
• Biotin
• FITC
• APC, Cy7
• PE
• APC
• More...
  • Cy3

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC, Cy7
  • PE
  • APC
  • Cy3

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CARD9 Antibody (clone OTI3F8) LS-C796172

Antibody:

CARD9 Mouse anti-Human Monoclonal (OTI3F8) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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CARD9 Antibody (aa237-536) LS-C379465

Antibody:

CARD9 Rabbit anti-Human Polyclonal (aa237-536) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

CARD9 Antibody (aa26-283) LS-C375022

Antibody:

CARD9 Rabbit anti-Human Polyclonal (aa26-283) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$318; 200 µl/$364; 500 µl/$518; 1 ml/$595; 2 ml/$822; 5 ml/$1,345

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CARD9 Antibody (aa26-283, Biotin) LS-C689560

Antibody:

CARD9 Rabbit anti-Human Polyclonal (aa26-283) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$329; 200 µl/$379; 500 µl/$549; 1 ml/$651; 2 ml/$886; 5 ml/$1,479

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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CARD9 Antibody LS-C807176

Antibody:

CARD9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

CARD9 Antibody LS-C401479

Antibody:

CARD9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

CARD9 Antibody LS-C404770

Antibody:

CARD9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

CARD9 Antibody (aa521-536) LS-C82960

Antibody:

CARD9 Rabbit anti-Human Polyclonal (aa521-536) Antibody

Reactivity:

Human

Applications:

ICC, WB

Format:

Unconjugated

Price:

100 µg/$539

Select

CARD9 Antibody LS-C660025

Antibody:

CARD9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

CARD9 Antibody LS-C306741

Antibody:

CARD9 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$705

Select

CARD9 Antibody LS-C836058

Antibody:

CARD9 Rabbit Polyclonal Antibody

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295

Select

CARD9 Antibody (aa467-516) LS-C116740

Antibody:

CARD9 Rabbit anti-Human Polyclonal (aa467-516) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

CARD9 Antibody (aa467-516, HRP) LS-C463621

Antibody:

CARD9 Rabbit anti-Human Polyclonal (aa467-516) (HRP) Antibody

Reactivity:

Horse, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

CARD9 Antibody (aa467-516, Biotin) LS-C463927

Antibody:

CARD9 Rabbit anti-Human Polyclonal (aa467-516) (Biotin) Antibody

Reactivity:

Horse, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

CARD9 Antibody (aa467-516, FITC) LS-C463620

Antibody:

CARD9 Rabbit anti-Human Polyclonal (aa467-516) (FITC) Antibody

Reactivity:

Horse, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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