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CARD16 / COP

caspase recruitment domain family, member 16

Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.

Gene Name: caspase recruitment domain family, member 16
Synonyms: CARD16, Caspase-1 inhibitor COP, COP1, CARD only protein, Pseudo-ICE
Target Sequences: NP_001017534.1 Q5EG05

☰ Filters
Antibodies (22)
Proteins (8)
Over-Expression Lysate (4)
Primary (22)
Recombinant (4)
CARD16 / COP (30)
Human (22)
IHC (1)
WB (21)
Flo (7)
ELISA (13)
IF (2)
Peptide-ELISA (1)
rabbit (14)
mouse (7)
goat (1)
IgG (14)
IgG2b,k (6)
monoclonal mc (6)
polyclonal pc (16)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (3)
Unconjugated (7)
aa37-65 (7)
aa1-98 (1)
aa85-97 (1)
No (30)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (5)
Human (6)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
Select
CARD16 / COP Mouse anti-Human Monoclonal (aa1-98) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
Select
CARD16 / COP Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
Select
CARD16 / COP Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
Select
CARD16 / COP Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
Select
CARD16 / COP Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
Select
CARD16 / COP Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
Select
CARD16 / COP Rabbit anti-Human Polyclonal (aa37-65) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
Select
CARD16 / COP Rabbit anti-Human Polyclonal (aa37-65) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
Select
CARD16 / COP Rabbit anti-Human Polyclonal (aa37-65) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
Select
CARD16 / COP Rabbit anti-Human Polyclonal (aa37-65) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
CARD16 / COP Rabbit anti-Human Polyclonal (aa37-65) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
Select
CARD16 / COP Rabbit anti-Human Polyclonal (aa37-65) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
CARD16 / COP Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using CARD16 Polyclonal Antibody at dilution of 1:55(×200)
Select
CARD16 / COP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CARD16 / COP Antibody - COP1 Antibody western blot of CEM,A549 cell line lysates (35 ug/lane). The COP1 antibody detected the COP1 protein (arrow).
Select
CARD16 / COP Rabbit anti-Human Polyclonal (aa37-65) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
Select
CARD16 / COP Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
CARD16 / COP Antibody - CARD16 / COP antibody immunofluorescence analysis of paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing mitochondrial staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).
Select
CARD16 / COP Goat anti-Human Polyclonal (aa85-97) Antibody
Human
IF, Peptide-ELISA
Unconjugated
100 µg/$503
Select
CARD16 / COP Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
CARD16 / COP Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
Select
CARD16 / COP Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
CARD16 / COP Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
Select
CARD16 / COP Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
Select
CARD16 / COP Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
CARD16 / COP Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CARD16 / COP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
10.6 kDa
20 µg/$150
CARD16 / COP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
22.4 kDa
20 µg/$150
Viewing 1-25 of 30 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).