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CAPNS1 / CAPN4

calpain, small subunit 1

CAPNS1 / CAPN4 is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants.

Gene Name: calpain, small subunit 1
Family/Subfamily: Protease Regulatory , Cysteine C2
Synonyms: CAPNS1, 30K, Calpain, small polypeptide, Calpain, small subunit 1, CANP small subunit, CAPN4, Calpain small polypeptide, CDPS, Calpain small subunit 1, CANP, CAPNS, CSS1, Calpain 4, small subunit (30K), Calpain regulatory subunit, CALPAIN4, CANPS
Target Sequences: NM_001749 NP_001740.1 P04632

☰ Filters
Antibodies (29)
Proteins (9)
ELISA Kits (5)
Development Kit (1)
Over-Expression Lysate (2)
Primary (29)
Recombinant (7)
Sandwich (4)
CAPNS1 / CAPN4 (43)
Human (32)
Mouse (14)
Rat (6)
Bat (3)
Bovine (4)
Chimpanzee (3)
Gibbon (3)
Monkey (3)
Pig (3)
Rabbit (3)
IHC (7)
IHC-P (3)
WB (23)
Flo (1)
ELISA (11)
ICC (1)
IF (2)
IP (2)
Peptide-ELISA (1)
RNAi (1)
rabbit (24)
mouse (5)
Product Group
DevKit DuoPlus (1)
IgG (12)
IgG1 (2)
IgG1,k (2)
monoclonal mc (4)
polyclonal pc (25)
3C4 (1)
AT1D11 (1)
96-Well Strip Plate (4)
Antibody Pair and Standard (1)
APC (1)
APC Conjugated (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (16)
aa1-268 (12)
C-Terminus (4)
No (43)
Cell Culture Supernatants (3)
Cell Lysates (3)
Plasma (1)
Serum (1)
Tissue Homogenates (5)
GST (1)
GST, N-terminus (1)
His (1)
His-GST (1)
His-SUMO (1)
Myc-DDK (Flag) (4)
Human (8)
293T Cells (1)
E. coli (3)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
CAPNS1 / CAPN4 Antibody - Immunofluorescence of monoclonal antibody to CAPNS1 on HeLa cell. [antibody concentration 20 ug/ml]
Select
CAPNS1 / CAPN4 Mouse anti-Human Monoclonal (3C4) Antibody
Rat, Human
ELISA, IF, RNAi, WB
Unconjugated
100 µg/$423
CAPNS1 / CAPN4 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
CAPNS1 / CAPN4 Antibody - Immunohistochemistry of paraffin-embedded human adrenal gland tissue at dilution 1:100
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CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
CAPNS1 / CAPN4 Antibody - ICC/IF analysis of CAPNS1 in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human CAPNS1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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CAPNS1 / CAPN4 Mouse anti-Human Monoclonal (AT1D11) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
CAPNS1 / CAPN4 Antibody - Immunohistochemistry of paraffin-embedded Human ovarian cancer using CAPNS1 Polyclonal Antibody at dilution of 1:60.
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CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
CAPNS1 / CAPN4 Antibody - Immunohistochemistry of paraffin-embedded human liver cancer tissue.
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CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CAPNS1 / CAPN4 Antibody - Immunohistochemistry of paraffin-embedded human adrenal gland tissue at dilution 1:100
Select
CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CAPNS1 / CAPN4 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
CAPNS1 / CAPN4 Mouse anti-Human Monoclonal Antibody
Bovine, Human
ELISA, IP, WB
Unconjugated
100 µg/$466
CAPNS1 / CAPN4 Antibody - Immunohistochemical analysis of Calpain reg staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
Select
CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CAPNS1 / CAPN4 Antibody - Immunofluorescence staining of A549 cells with CAPNS1 Antibody at 1:533, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Select
CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal (aa1-268) Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal (aa1-268) (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal (aa1-268) (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal (aa1-268) (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
CAPNS1 / CAPN4 Mouse anti-Human Monoclonal Antibody
Human
IP
Unconjugated
1 ml/$466
CAPNS1 / CAPN4 Antibody - CAPNS1 / Calpain S1 antibody Western blot of Fetal Lung lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CAPNS1 / CAPN4 Antibody - CAPNS1 / Calpain S1 antibody Western blot of Fetal Lung lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Bovine, Pig, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
CAPNS1 / CAPN4 Antibody - CAPNS1 / Calpain S1 antibody Western blot of Fetal Lung lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Bovine, Pig, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
CAPNS1 / CAPN4 Antibody - CAPNS1 / Calpain S1 antibody Western blot of Fetal Lung lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Bovine, Pig, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
CAPNS1 / CAPN4 Antibody - Western blot of CAPNS1 / CAPN4 antibody.
Select
CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal (aa1-268) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
CAPNS1 / CAPN4 Antibody - Western blot of CAPNS1 / CAPN4 antibody.
Select
CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal (aa1-268) (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
CAPNS1 / CAPN4 Antibody - Western blot of CAPNS1 / CAPN4 antibody.
Select
CAPNS1 / CAPN4 Rabbit anti-Human Polyclonal (aa1-268) (Cy3) Antibody
Mouse, Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Select
CAPNS1 / CAPN4 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-25 of 43 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).