Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CAPN9 Antibody, Calpain 9 Antibody, GC36 Antibody, NCL-4 Antibody, NCL4 Antibody, Protein CG36 Antibody, New calpain 4 Antibody, Calpain 9 (nCL-4) Antibody, Calpain-9 Antibody, Novel calpain large subunit-4 Antibody
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress.
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-CAPN9 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CAPN9 mouse monoclonal antibody.
Anti-CAPN9 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CAPN9.
Western blot of extracts (35 ug) from 9 different cell lines by using anti-CAPN9 monoclonal antibody.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CAPN9 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CAPN9.
Flow cytometry of Jurkat cells, using anti-CAPN9 antibody (Red), compared to a nonspecific negative control antibody (Blue).