Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal (IgG1) to Bovine CAPN1 / Calpain 1
Bovine, Human, Rat, Pig
ICC, Western blot, Immunoprecipitation
Bovine CAPN1 / Calpain 1
Bovine, Human, Rat, Pig (tested or 100% immunogen sequence identity)
Western blot (1:1000)
Specificity and Use
CAPN1 / Calpain 1 antibody was raised against purified bovine mu-calpain.
Recognizes an epitope in domain II (aa 245-265) of mu-calpain from several mammalian sources (e. g. human, rat, pig, bovine). Detects a band of ~80kD by Western blot. Does not cross-react with m-calpain, n-calpain, calmodulin or calpastatin.
Suitable for use in Immunocytochemistry, Western Blot. Immunocytochemistry: 1:25. Western Blot: 1:1000. Note: Not recommended for Immunoprecipitation.
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.