Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Rat (tested or 100% immunogen sequence identity)
Western blot (1:1000 - 1:5000)
ELISA (1:100 - 1:1000)
IHC - Paraffin
Specificity and Use
CAMK2B / CaMKII Beta antibody was raised against this antibody was developed against a synthetic peptide corresponding to amino acids 499-513 (VRRGSGTPEAEAPRQ) of human CAMKIIb. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (80%).
Human CAMKII beta (CAMK2B) is a 664 amino acid protein. However, several isoforms of varying amino acid sizes have been described for CAMKII beta. Researchers are encouraged to utilize the sequence information used for immunogen (VRRGSGTPEAEAPRQ) to gain additional information about these isoforms and various molecular weights which may be detected by western blot analysis.
50% glycerol and 0.025% sodium azide.
Store at -20°C. Aliquot to avoid freeze/thaw cycles. Store undiluted.
CAMK2B Antibody, Beta-subunit of CaMK II Antibody, Cam kinase II beta Antibody, CaMK IIbeta Antibody, CaM-kinase II beta chain Antibody, CAMKB Antibody, Beta CaMK II Antibody, CaM kinase II beta subunit Antibody, CaM kinase II subunit beta Antibody, CaM kinase IIbeta Antibody, CAM2 Antibody, Camk ii beta Antibody, CAMK2 Antibody, CaMKII beta Antibody, CaMK-II subunit beta Antibody, CaMKIIbeta Antibody
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner.