Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human CALR / Calreticulin
IHC - Paraffin, Western blot, ELISA
Human CALR / Calreticulin
Human, Monkey (tested or 100% immunogen sequence identity)
IHC - Paraffin
Western blot (1:500 - 1:2000)
IHC - Paraffin
Specificity and Use
CALR / Calreticulin antibody was raised against synthetic peptide from human CALR / Calreticulin. Percent identity by BLAST analysis: Human, Gibbon, Macaque, Monkey, Marmoset, Green monkey (100%); Gorilla (92%); Bat, Horse (85%).
Synthetic peptide corresponding to aa(EEEDVPGQAKDELC)of human Calreticulin
PBS, pH 7.4, 0.03% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors.