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Anti-Calprotectin Antibody (clone 27E10, FITC) LS-C96225

Note: This antibody replaces LS-C121136

Ordering

Wt. Vol. Conc. Price
200 µg - - $620
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
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Most Popular Calprotectin Antibodies

Anti-Calprotectin Antibody (clone 27E10, Biotin) LS-C140077
Mouse Monoclonal [clone 27E10] (IgG1) to Human Calprotectin
Human
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Biotin Conjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 27E10]
Human
FITC Conjugated

Details

Calprotectin
Mouse
Human (tested or 100% immunogen sequence identity)
Monoclonal [27E10]
Fluorescein
Affinity purified
Unmodified

Specificity and Use

Calprotectin antibody was raised against cultured human monocytes
The antigen is MRP8/14 (calprotectin), the epitope involves parts of both subunits MRP8 and MRP14. Antigen distribution: Isolated cells: Monocytes carry the antigen both on the surface and intracellularly, granulocytes exhibit it only intracellularly. Up to 80% of monocytes in early cultures (24- 48h) are positive. No reaction has been seen with lymphocytes or platelets. Tissue sections: The antigen is found in macrophages in the red pulp of the spleen and liver. It is strongly expressed in macrophages from acute inflamed tissues (peridontitis, contact excema, urticaria, erythrodermia) where some endothelial and epidermal cells may also express this antigen. It is normally absent on resident mononuclear phagocytes in healthy tissues (skin, gut, thymus). Specificity: Human: subpopulation of macrophages, monocytes and granulocytes; peripheral blood monocytes carry the antigen extra- and intracellularly, neutrophils only intracellularly. Other: subpopulation of macrophages of rhesus monkey and bovine tissues. The antibody does not react with swine tissues.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS pH 7.2, 10mg/ml BSA, 0.1% sodium azide
Store at 4°C.
For research use only.

About Calprotectin


Requested From: United States
Date Requested: 12/7/2016

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