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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CALD1 / Caldesmon Antibody LS‑C41799
Antibody
Caldesmon antibody LS-C41799 is an unconjugated mouse monoclonal antibody to Caldesmon (CALD1) from human, chicken and duck. Validated for ELISA and WB.
Catalog
Size
Price
LS-C41799-200
200 µg (2 mg/ml)
Unavailable

Popular CALD1 / Caldesmon Products

Antibody
Species: Human
Applications: IHC, Immunofluorescence, Western blot, Immunoprecipitation
Formalin-fixed, paraffin-embedded human uterus stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of smooth muscles. This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Anti-CALD1 / Caldesmon antibody IHC of human prostate, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6995 dilution 1:100.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-Caldesmon antibody IHC of human prostate, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7961 dilution 5-10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Antibody
Species: Human
Applications: IHC, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry

Product Description

Caldesmon antibody LS-C41799 is an unconjugated mouse monoclonal antibody to Caldesmon (CALD1) from human, chicken and duck. Validated for ELISA and WB.
About CALD1 / Caldesmon
Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Q05682 NM_004342 NP_004333.1

CALD1 Antibody, Caldesmon Antibody, Caldesmon 1 Antibody, HCAD Antibody, LCAD Antibody, H-CAD Antibody, NAG22 Antibody, CDM Antibody, L-CAD Antibody


Specifications

Target
Duck CALD1 / Caldesmon
Host
Mouse
Reactivity
Duck, Human, Chicken (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot
  • ELISA
Immunogen
Duck gizzard caldesmon (heavy type).
Specificity
Reacts with the high molecular weight (120-150 kD) and a low molecular weight (71-80 kD) forms of caldesmon, an actin interacting and calmodulin binding protein found in smooth muscle and other cell types.
Presentation
PBS, pH 7.2, 0.09% sodium azide.
Storage
4°C or -20°C, Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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