Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Duck, Human, Chicken (tested or 100% immunogen sequence identity)
Protein A purified
Specificity and Use
CALD1 / Caldesmon antibody was raised against duck gizzard caldesmon (heavy type).
Reacts with the high molecular weight (120-150 kD) and a low molecular weight (71-80 kD) forms of caldesmon, an actin interacting and calmodulin binding protein found in smooth muscle and other cell types.
PBS, pH 7.2, 0.09% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin.