Human CA2 / Carbonic Anhydrase II

Sheep

Human (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Purified

Unmodified

Purified human carbonic anhydrase II (CAII) prepared from erythrocytes.

Recognizes human carbonic anhydrase II, also known as Carbonate dehydratase II or Carbonic anhydrase C. Carbonic anhydrase II is a 259 amino acid ~30 kD enzyme essential for bone resorption and osteoclast differrentiation. Mutations in the CA2 gene has been identified as the cause of Osteopetrosis, autosomal recessive 3, a rare disease characterized by particularly dense bone, cerebral calcification and renal tubular acidisis. Product identity is confirmed by double diffusion vs. human CAII. No reactivity is seen in immunodiffusion against CAI.

• Immunofluorescence
• Western blot (1:1000)
• Immunodiffusion

GBS, 1 mM EDTA, 0.1% EACA, 0.09% Sodium Azide, 0.01% Benzamidine

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P00918 NCBI: NM_000067 NP_000058.1