Mouse C5AR1 / CD88 / C5a Receptor

Rat

Mouse (tested or 100% immunogen sequence identity)

IgG2b Monoclonal

20/70

Unconjugated

Protein G purified

Unmodified

RBL-2H3 transfected cells expressing murine C5aR

Recognizes murine CD88, a 45kD G-protein coupled cell surface receptor, which is otherwise known as C5aR. The CD88 molecule functions as a receptor for the complement component C5a, which is a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes. Clone 20/70 has been reported to block the binding of the C5a to murine CD88. XXX recommend the use of MCA2457EL for this purpose.

• Flow Cytometry (1:50 - 1:100)

• IHC - Frozen

Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P21730 NCBI: NM_001736 NP_001727.1