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Anti-c-Src Kinase / CSK Antibody LS-C6233

Ordering

Wt. Vol. Conc. Price
100 µg - - $650
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Mouse Monoclonal (IgG1) to Human c-Src Kinase / CSK
Human, Mouse
Western blot, Immunoprecipitation
Unconjugated

Details

Human c-Src Kinase / CSK
Mouse
Human, Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Protein A purified

Applications

Western blot (1:125 - 1:150), Immunoprecipitation

Specificity and Use

c-Src Kinase / CSK antibody was raised against bacterially expressed recombinant fragment of human Csk corresponding to amino acids 330-450.
Recognizes C-terminal human src kinase (Csk), a cytosolic 50kD non-receptor protein tyrosine kinase, which is ubiquitously expressed and functions as an essential negative regulator of src family kinases (SFKs). Species cross-reactivity: mouse.
Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 1:125-1:150. Detects a band at ~50kD in mouse EL-4 cell lysates.

Packaging

PBS, pH 7.4, 0.1% sodium azide, 40% glycerol.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About c-Src Kinase / CSK

P41240 NM_004383 NP_004374.1

CSK Antibody, C-src tyrosine kinase Antibody, C-Src kinase Antibody, Protein-tyrosine kinase CYL Antibody, Tyrosine-protein kinase CSK Antibody, C-SRC Antibody, Cytoplasmic tyrosine kinase Antibody

Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation.

Requested From: United States
Date Requested: 9/30/2016

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