c-Src Kinase / CSK

c-src tyrosine kinase

Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.

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Products

Antibodies (73)

Proteins (17)

ELISA Kits (8)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Custom (4)

Over-Expression Lysate (5)

Primary (73)

Recombinant (12)

Sandwich (2)

Target

c-Src Kinase / CSK (98)

Reactivity

Human (75)

Mouse (40)

Rat (28)

Bat (4)

Bovine (5)

Chicken (5)

Chimpanzee (3)

Dog (4)

Gibbon (3)

Guinea pig (3)

Hamster (3)

Horse (3)

Monkey (5)

Non-Human Primate (1)

Pig (4)

Zebrafish (4)

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Application

IHC (11)

IHC-P (6)

WB (72)

Flo (3)

ELISA (28)

ICC (5)

IF (10)

IP (6)

Peptide-ELISA (7)

RNAi (1)

Host

rabbit (57)

mouse (13)

goat (3)

Product Group

IHCPlus (2)

Isotype

IgG (35)

IgG1 (6)

IgG1,k (1)

IgG2a (1)

IgG2b (2)

IgG2b,k (1)

Clonality

monoclonal mc (14)

polyclonal pc (59)

Clone

3A3 (1)

5F3 (2)

AT7C6 (1)

CSK-04 (2)

Format

96-Well Microplate (2)

96-Well Strip Plate (6)

APC (1)

APC Conjugated (4)

Azide-free (2)

Biotin Conjugated (6)

Concentrated (1)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (4)

Unconjugated (47)

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Epitope

aa243-438 (8)

aa33-61 (7)

aa377-404 (7)

aa323-372 (4)

pSer364 (4)

300-380 aa (2)

aa330-450 (2)

1-80 aa, N-terminal (1)

Asn63 (1)

C-Terminus (1)

Leu558 (1)

N-Terminus (1)

Val399 (1)

aa164-197 (1)

aa2-204 (1)

aa31-80 (1)

aa330-379 (1)

aa375-425 (1)

aa400-450 (1)

aa438-450 (1)

aa67-101 (1)

p364 (1)

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Publications

No (97)

Yes (1)

Sample Type

Adherent Cell Cultures (2)

Plasma (2)

Serum (2)

Tissue Homogenates (1)

Tag

6His, N-terminus (2)

GST (1)

GST, N-terminus (2)

His (1)

His-GST (3)

His-T7 (1)

Myc-DDK (Flag) (6)

Species

Human (12)

Mouse (3)

Source

293T Cells (2)

Baculovirus (3)

E. coli (3)

HEK 293 Cells (5)

Insect Cells (2)

Wheat Germ Extract (2)

Purification

Purified (6)

Low Endotoxin Level

Low endotoxin level (5)

Select

Human c-Src Kinase / CSK (Sandwich ELISA) ELISA Kit - LS-F11230

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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c-Src Kinase / CSK Antibody (clone 5F3) LS-C169267

Antibody:

c-Src Kinase / CSK Mouse anti-Human Monoclonal (5F3) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, WB

Format:

Unconjugated

Price:

100 µl/$435

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IHC-plus™ c-Src Kinase / CSK Antibody (aa400-450) LS-B14204

(4.0) Rating

Antibody:

c-Src Kinase / CSK Rabbit anti-Human Polyclonal (aa400-450) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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c-Src Kinase / CSK Antibody (aa377-404, Azide-free, HRP) LS-C255517

Antibody:

c-Src Kinase / CSK Rabbit anti-Human Polyclonal (aa377-404) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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c-Src Kinase / CSK Antibody (clone 5F3) LS-C758885

Antibody:

c-Src Kinase / CSK Mouse anti-Human Monoclonal (5F3) Antibody

Reactivity:

Mouse, Rat, Non-Human Primate, Human

Applications:

Flo, ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$541

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c-Src Kinase / CSK Antibody LS-C812554

Antibody:

c-Src Kinase / CSK Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, Flo, IF, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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c-Src Kinase / CSK Antibody (Val399) LS-C63922

Antibody:

c-Src Kinase / CSK Rabbit anti-Human Monoclonal (Val399) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$688

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IHC-plus™ c-Src Kinase / CSK Antibody (aa375-425) LS-B14203

(4.0) Rating

Antibody:

c-Src Kinase / CSK Rabbit anti-Human Polyclonal (aa375-425) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP

Format:

Unconjugated

Price:

50 µl/$460

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c-Src Kinase / CSK Antibody LS-C664822

Antibody:

c-Src Kinase / CSK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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c-Src Kinase / CSK Antibody (clone 3A3) LS-C133138

Antibody:

c-Src Kinase / CSK Mouse anti-Human Monoclonal (3A3) Antibody

Reactivity:

Human

Applications:

ELISA, IP, RNAi, WB

Format:

Unconjugated

Price:

100 µg/$423

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Human c-Src Kinase / CSK Protein (Recombinant 6His, N-terminus) (Ser2-Leu450) - LS-G26650

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

50 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Mouse/Human/Rat c-Src Kinase / CSK (Cell-Based ELISA) ELISA Kit - LS-F1918

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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c-Src Kinase / CSK Antibody LS-C664823

Antibody:

c-Src Kinase / CSK Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$351

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c-Src Kinase / CSK Antibody (aa2-204) LS-C343964

Antibody:

c-Src Kinase / CSK Rabbit anti-Human Polyclonal (aa2-204) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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c-Src Kinase / CSK Antibody (1-80 aa, N-terminal) LS-C382925

Antibody:

c-Src Kinase / CSK Rabbit anti-Human Polyclonal (1-80 aa, N-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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c-Src Kinase / CSK Antibody (clone AT7C6) LS-C755438

Antibody:

c-Src Kinase / CSK Mouse anti-Human Monoclonal (AT7C6) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, WB

Format:

Unconjugated

Price:

50 µl/$303; 100 µl/$365

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c-Src Kinase / CSK Antibody (300-380 aa) LS-C380896

Antibody:

c-Src Kinase / CSK Rabbit anti-Human Polyclonal (300-380 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

c-Src Kinase / CSK Antibody LS-C822726

Antibody:

c-Src Kinase / CSK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

c-Src Kinase / CSK Antibody (300-380 aa) LS-C382924

Antibody:

c-Src Kinase / CSK Rabbit anti-Human Polyclonal (300-380 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

c-Src Kinase / CSK Antibody (p364) LS-C821778

Antibody:

c-Src Kinase / CSK Rabbit anti-Human Polyclonal (p364) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

c-Src Kinase / CSK Antibody (aa330-450, clone CSK-04) LS-C46038

Antibody:

c-Src Kinase / CSK Mouse anti-Human Monoclonal (aa330-450) (CSK-04) Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

0.1 ml/$337

Select

c-Src Kinase / CSK Antibody (aa31-80) LS-C118888

Antibody:

c-Src Kinase / CSK Rabbit anti-Human Polyclonal (aa31-80) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

c-Src Kinase / CSK Antibody LS-C809237

Antibody:

c-Src Kinase / CSK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

c-Src Kinase / CSK Antibody (aa330-379) LS-C117597

Antibody:

c-Src Kinase / CSK Rabbit anti-Human Polyclonal (aa330-379) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

c-Src Kinase / CSK Antibody LS-C342022

Antibody:

c-Src Kinase / CSK Mouse anti-Human Monoclonal Antibody

Reactivity:

Rat, Human

Applications:

ICC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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