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c‑Src Kinase / CSK Antibody (aa330‑450, clone CSK‑04) LS‑C204153
CSK antibody LS-C204153 is an unconjugated mouse monoclonal antibody to human CSK (c-Src Kinase). Validated for IP and WB.
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Review This ProductPopular c-Src Kinase / CSK Products
Species:
Human, Mouse, Rat
Applications:
Western blot
Species:
Human
Applications:
Flow Cytometry, ELISA
Species:
Human, Mouse
Applications:
Western blot, ELISA
Species:
Human, Mouse, Rat, Bovine, Dog, Horse, Chicken
Applications:
IHC, IHC - Paraffin, Immunoprecipitation
Species:
Human, Monkey, Mouse, Dog, Pig
Applications:
IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Product Description
CSK antibody LS-C204153 is an unconjugated mouse monoclonal antibody to human CSK (c-Src Kinase). Validated for IP and WB.
About c-Src Kinase / CSK
Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation.
P41240
NM_004383
NP_004374.1
CSK Antibody, C-src tyrosine kinase Antibody, C-Src kinase Antibody, Protein-tyrosine kinase CYL Antibody, Tyrosine-protein kinase CSK Antibody, C-SRC Antibody, Cytoplasmic tyrosine kinase Antibody
Specifications
Target
Human c-Src Kinase / CSK
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
[CSK-04]
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
- Western blot
- Immunoprecipitation
Immunogen
Bacterially expressed recombinant fragment of human Csk corresponding to aa 330-450.
Epitope
aa330-450
Specificity
C-terminal Src kinase (Csk) is a non-receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C-terminal tyrosine of Src family kinases thereby down-regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft-associated protein PAG (Csk-binding protein).
Presentation
PBS, pH 7.4, 15 mM sodium azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
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Requested From:
Date Requested: 6/20/2018
Date Requested: 6/20/2018
