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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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c‑Src Kinase / CSK Antibody (aa330‑450, clone CSK‑04) LS‑C204153
Antibody
CSK antibody LS-C204153 is an unconjugated mouse monoclonal antibody to human CSK (c-Src Kinase). Validated for IP and WB.
Catalog
Size
Price
LS-C204153-100
100 µg (1 mg/ml)
Unavailable

Popular c-Src Kinase / CSK Products

Antibody
Species: Human, Mouse, Rat
Applications: Western blot
Immunofluorescence of U251 cells using CSK mouse monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Species: Human
Applications: Flow Cytometry, ELISA
Antibody
Species: Human, Mouse
Applications: Western blot, ELISA
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Rat, Bovine, Dog, Horse, Chicken
Applications: IHC, IHC - Paraffin, Immunoprecipitation
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Monkey, Mouse, Dog, Pig
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation

Product Description

CSK antibody LS-C204153 is an unconjugated mouse monoclonal antibody to human CSK (c-Src Kinase). Validated for IP and WB.
About c-Src Kinase / CSK
Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. P41240 NM_004383 NP_004374.1

CSK Antibody, C-src tyrosine kinase Antibody, C-Src kinase Antibody, Protein-tyrosine kinase CYL Antibody, Tyrosine-protein kinase CSK Antibody, C-SRC Antibody, Cytoplasmic tyrosine kinase Antibody


Specifications

Target
Human c-Src Kinase / CSK
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [CSK-04]
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • Western blot
  • Immunoprecipitation
Immunogen
Bacterially expressed recombinant fragment of human Csk corresponding to aa 330-450.
Epitope
aa330-450
Specificity
C-terminal Src kinase (Csk) is a non-receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C-terminal tyrosine of Src family kinases thereby down-regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft-associated protein PAG (Csk-binding protein).
Presentation
PBS, pH 7.4, 15 mM sodium azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/20/2018

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