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Anti-c-Met Antibody (phospho-Tyr1230/Tyr1234/Tyr1235) LS-C16513

Catalog Size Price
LS-C16513-10 10 blot Unavailable

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100% Guaranteed
Rabbit Polyclonal to Human c-Met
Human, Mouse
Western blot, ELISA


Human c-Met
Human, Mouse (tested or 100% immunogen sequence identity)
Rat (at least 90% immunogen sequence identity)
Affinity purified


  • Western blot (1:1000)

Specificity and Use

c-Met antibody was raised against synthetic phosphopeptide derived from the region of human c-Met that contains tyrosines 1230, 1234 and 1235. The sequence is conserved in mouse and rat.
Recognizes human and mouse c-Met. c-Met has not been tested. The phosphospecific antibody that has been generated does not distinguish between the dually (pYpY1234/1235) and triply (pYpYpY1230/1234/1235) phosphorylated forms of c-Met, both of which are likely to represent activated forms of this receptor. Species sequence homology: rat 100%.
Suitable for use in Western Blot and ELISA. Western Blot: 1:1000. Positive control: 293T human kidney cells transiently transfected with human Met cDNA, stimulated with HGF; Mouse myeloma (SP-1) cells stimulated with HGF; A431 cells stimulated with EGF.


Dulbecco's PBS (without Mg2+, Ca2+), 1 mg/ml BSA (IgG, protease free), pH 7.3, 0.05% sodium azide, 50% glycerol.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About c-Met

P08581 NM_000245 NP_000236.2

MET Antibody, AUTS9 Antibody, C-Met Antibody, HGF/SF receptor Antibody, HGFR Antibody, Met kinase Antibody, Proto-oncogene c-Met Antibody, Scatter factor receptor Antibody, SF receptor Antibody, HGF receptor Antibody, RCCP2 Antibody, Tyrosine-protein kinase Met Antibody

Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules.

Requested From: 
Date Requested: 3/24/2018

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