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| Catalog Number | Size | Price |
|---|---|---|
| LS-B2812-50 | 50 µl (1.14 mg/ml) | $615 |
IHC‑plus™ Monoclonal Mouse anti‑Human c‑Met Antibody (Cytoplasmic Domain, IHC) LS‑B2812
IHC‑plus™ Monoclonal Mouse anti‑Human c‑Met Antibody (Cytoplasmic Domain, IHC) LS‑B2812
Note: This antibody replaces LS-C16508
Antibody:
c-Met Mouse anti-Human Monoclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P, IHC-Fr
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
c-Met Mouse anti-Human Monoclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P, IHC-Fr
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
C-Met antibody LS-B2812 is an unconjugated mouse monoclonal antibody to human c-Met (Cytoplasmic Domain). Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Target
Human c-Met
Synonyms
MET | AUTS9 | C-Met | HGF/SF receptor | HGFR | Met kinase | Proto-oncogene c-Met | Scatter factor receptor | SF receptor | HGF receptor | RCCP2 | Tyrosine-protein kinase Met
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG2a
Monoclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Immunogen
Synthetic peptide derived from cytoplasmic domain of human c-Met protein
Epitope
Cytoplasmic Domain
Specificity
Recognizes c-Met.
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- IHC - Frozen (1:50)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B2812 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2812 was determined to be 10 ug/ml. Positive control: Breast cancer.
Presentation
PBS, pH 7.4, 0.09% Sodium Azide, 1% BSA
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About c-Met
Validation
Anti-c-Met antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-c-Met antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ c-Met Antibody (Cytoplasmic Domain) for IHC LS-B2812 has an LSBio Rating of
Publications (4.2)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (3)
MET Gene Status in Malignant Mesothelioma Using Fluorescent In Situ Hybridization. Varesano S, Salvi S, Boccardo S, Ravetti JL, Pistillo MP, Canessa PA, Ferro P, Fedeli F, Roncella S. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2016 February;11:e28-e30.
A Case of Atypical Carcinoid: Harboring Variant 3a/b EML4-ALK Rearrangement. Fukuizumi A, Akagi K, Sakai H. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2015 October;10:e104-e106.
EGFR Status in Mesothelioma: Possible Implications for the Efficacy of Anti-EGFR and Anti-MET Therapies. Sandra Salvi, Serena Varesano, Simona Boccardo, Jean Louis Ravetti, Pier Aldo Canessa, Maria Pia Pistillo, Paola Ferro, Franco Fedeli, Silvio Roncella. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2016 Jun;11:e78-80.
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Featured Products
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human, Mouse, Rat
Applications:
Western blot, Immunoprecipitation, ELISA
Reactivity:
Human, Mouse, Rat
Range:
Positive/Negative
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/16/2024
Date Requested: 4/16/2024
