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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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c‑Kit / CD117 Antibody LS‑C43512
Note: This antibody replaces LS-C57316
Antibody
CD117 antibody LS-C43512 is an unconjugated rat monoclonal antibody to mouse CD117 (c-Kit). Validated for Flow.
Catalog
Size
Price
LS-C43512-250
250 µg (1 mg/ml)
Unavailable

Popular c-Kit / CD117 Products

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Immunofluorescence staining of rat skin (epidermis). c-KIT detection was done using LS-C78828 (red color). DAPI was used to counterstain cell nuclei (blue color). Working dilution: 1:100-1:300.
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Antibody
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Product Description

CD117 antibody LS-C43512 is an unconjugated rat monoclonal antibody to mouse CD117 (c-Kit). Validated for Flow.
About c-Kit / CD117
Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. P10721 NM_000222 NP_000213.1

KIT Antibody, C-Kit Antibody, CD117 Antibody, PBT Antibody, Piebald trait Antibody, Piebald trait protein Antibody, Proto-oncogene c-Kit Antibody, SCFR Antibody, Soluble KIT variant 1 Antibody, Tyrosine-protein kinase Kit Antibody, p145 c-kit Antibody, CD117 antigen Antibody


Specifications

Target
Mouse c-Kit / CD117
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Flow Cytometry (1:50 - 1:200)
Immunogen
c-Kit / CD117 antibody was raised against iL-3 dependent mast cells.
Specificity
Recognizes mouse CD117, a 150kD cell surface molecule that is otherwise known as the Kit, or c-kit, receptor. Recognizes an epitope within the extracellular region of CD117. In mice, CD117 is predominantly expressed on multipotent hematopoietic stem cells from the adult bone marrow and fetal liver.
Usage
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Presentation
PBS, pH 7.4, 0.09% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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