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Anti-c-Kit / CD117 Antibody LS-C43512

Note: This antibody replaces LS-C57316
Catalog Size Price
LS-C43512-250 250 µg (1 mg/ml) Unavailable

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100% Guaranteed
Rat Monoclonal (IgG2b) to Mouse c-Kit / CD117
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Flow Cytometry
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Details

Mouse c-Kit / CD117
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG2b Monoclonal
Unconjugated
Protein G purified
Unmodified

Applications

Flow Cytometry (1:50 - 1:200)

Specificity and Use

c-Kit / CD117 antibody was raised against iL-3 dependent mast cells.
Recognizes mouse CD117, a 150kD cell surface molecule that is otherwise known as the Kit, or c-kit, receptor. Recognizes an epitope within the extracellular region of CD117. In mice, CD117 is predominantly expressed on multipotent hematopoietic stem cells from the adult bone marrow and fetal liver.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About c-Kit / CD117

P10721 NM_000222 NP_000213.1

KIT Antibody, C-Kit Antibody, CD117 Antibody, PBT Antibody, Piebald trait Antibody, Piebald trait protein Antibody, Proto-oncogene c-Kit Antibody, SCFR Antibody, Soluble KIT variant 1 Antibody, Tyrosine-protein kinase Kit Antibody, p145 c-kit Antibody, CD117 antigen Antibody

Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL.

Requested From: 
Date Requested: 12/13/2017

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