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Human c-Kit / CD117 | |
Mouse | |
Human (tested or 100% immunogen sequence identity) | |
IgG1,k Monoclonal [YB5.B8] | |
Phycoerythrin | |
Affinity purified | |
Unmodified |
Flow Cytometry |
c-Kit / CD117 antibody was raised against human KIT | |
The YB5. B8 antibody has been tested by flow cytometric analysis of the TF-1 cell line, a human erythroleukemia cell line. This can be used at 5 ul (0.25 ug)/per test. A test is defined as the amount (ug)/test of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. |
PBS, pH 7.2, 150 mM sodium chloride, 0.09% sodium azide, 0.2% BSA | |
Store at +4°C. Do not freeze. Protect from light. | |
For research use only. |
KIT Antibody, C-Kit Antibody, CD117 Antibody, PBT Antibody, Piebald trait Antibody, Piebald trait protein Antibody, Proto-oncogene c-Kit Antibody, SCFR Antibody, Soluble KIT variant 1 Antibody, Tyrosine-protein kinase Kit Antibody, p145 c-kit Antibody, CD117 antigen Antibody
Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL.
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