Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone NU-c-kit] (IgG) to Human c-Kit / CD117
Human c-Kit / CD117
Human (tested or 100% immunogen sequence identity)
IgG Monoclonal [NU-c-kit]
Protein A/G purified
Specificity and Use
c-Kit / CD117 antibody was raised against transfected cells with c-kit DNA in human leukemia cells (UT-7).
Detects human Caspase-7 by Western blot. Optimal concentration should be evaluated by serial dilutions. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, 0.08% Sodium Azide
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL.