Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone X1] (IgG2b,k) to Human c-Kit / CD117
IHC - Paraffin, Western blot, ELISA
Mouse Monoclonal [clone 104D2] (IgG1) to Human c-Kit / CD117
Human, Bovine, Primate
Human c-Kit / CD117
Human, Bovine, Primate (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [104D2]
Protein A purified
Specificity and Use
c-Kit / CD117 antibody was raised against mOLM-1 megakaryocytic cells.
Monoclonal antibody 104D2 detects extracellular part of CD117 / c-Kit protooncogene.
The reagent is designed for Flow Cytometry analysis of human blood cells using 10 ul reagent / 100 ul of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, 0.2% BSA, 0.02% sodium azide.
Store in the dark at 2-8 C. Do not freeze. Avoid prolonged exposure to light.
Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL.