Human c-Kit / CD117

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1,k Monoclonal

KIT/982

Unconjugated

Protein G purified

Unmodified. Also available Azide-free, BSA-free.

Recombinant human fragment around amino acids 100-300.

aa100-300

Human C-Kit / CD117

• IHC
• IHC - Frozen (2 - 4 µg/ml)
• Immunofluorescence (0.5 - 1 µg/ml)
• Western blot
• Flow Cytometry (0.5 - 1 µg/10E6 cells)

This mAb recognizes a protein of 145kDa, identified as CD117/p145kit/c-Kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117/c-Kit has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117/c-Kit is also useful in recognizing myeloblasts in bone marrow biopsy and clot section. Optimal dilution of the c-Kit antibody should be determined by the researcher.

1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P10721 NCBI: NM_000222 NP_000213.1