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Anti-c-CBL Antibody (clone 2111C3a) LS-C184440

Ordering

Wt. Vol. Conc. Price
50 µg - 0.1 mg/ml $325
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular c-CBL Antibodies

Anti-c-CBL Antibody (clone 3B12) IHC-plus™ LS-B11866
Mouse Monoclonal [clone 3B12] (IgG1) to Human c-CBL
Human, Mouse, Rat
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 2111C3a] (IgG1) to Human c-CBL
Human
ICC, Western blot, Dot Blot
Unconjugated

Details

Human c-CBL
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [2111C3a]
Unconjugated
Protein G purified
Unmodified

Applications

  • ICC
  • Western blot (0.2 - 2 µg/ml)
  • Dot Blot

Specificity and Use

c-CBL antibody was raised against recombinant Human Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (Cbl).
Human CBL

Packaging

PBS, pH 7.4, 1% BSA, 0.05% sodium azide
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About c-CBL

P22681 NM_005188 NP_005179.2

CBL Antibody, C-CBL Antibody, Oncogene CBL2 Antibody, RING finger protein 55 Antibody, Proto-oncogene c-Cbl Antibody, RNF55 Antibody, CBL2 Antibody, FRA11B Antibody, NSLL Antibody

Adapter protein that functions as a negative regulator of many signaling pathways that are triggered by activation of cell surface receptors. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including KIT, FLT1, FGFR1, FGFR2, PDGFRA, PDGFRB, EGFR, CSF1R, EPHA8 and KDR and terminates signaling.

Western blot

Western blot
Western blot of immunized recombinant protein using CBL antibody.
 

Requested From: United States
Date Requested: 12/7/2016

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