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Anti-c-CBL Antibody (clone 2111C3a) LS-C184440

Catalog Size Price
LS-C184440-50 50 µg (0.1 mg/ml) Unavailable

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100% Guaranteed
Mouse Monoclonal [clone 2111C3a] (IgG1) to Human c-CBL
Human
ICC, Western blot, Dot Blot
Unconjugated

Details

Human c-CBL
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [2111C3a]
Unconjugated
Protein G purified
Unmodified

Applications

  • ICC
  • Western blot (0.2 - 2 µg/ml)
  • Dot Blot

Specificity and Use

c-CBL antibody was raised against recombinant Human Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (Cbl).
Human CBL

Packaging

PBS, pH 7.4, 1% BSA, 0.05% sodium azide
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About c-CBL

P22681 NM_005188 NP_005179.2

CBL Antibody, C-CBL Antibody, Oncogene CBL2 Antibody, RING finger protein 55 Antibody, Proto-oncogene c-Cbl Antibody, RNF55 Antibody, CBL2 Antibody, FRA11B Antibody, NSLL Antibody

Adapter protein that functions as a negative regulator of many signaling pathways that are triggered by activation of cell surface receptors. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including KIT, FLT1, FGFR1, FGFR2, PDGFRA, PDGFRB, EGFR, CSF1R, EPHA8 and KDR and terminates signaling.

Western blot

Western blot
Western blot of immunized recombinant protein using CBL antibody.

Requested From: 
Date Requested: 12/15/2017

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