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Anti-BUB1B / BubR1 Antibody (Thr368) LS-C176888

Catalog Size Price
LS-C176888-100 100 µl Unavailable

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49 BUB1B / BubR1 Antibodies

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100% Guaranteed
Rabbit Polyclonal to Human BUB1B / BubR1
Human, Mouse
Western blot
Unconjugated

Details

Human BUB1B / BubR1
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot

Specificity and Use

BUB1B / BubR1 antibody was raised against synthetic peptide around Thr368 of human BUBR1
Thr368
Human BUBR1

Packaging

PBS, pH 7.2, 0.05% sodium azide
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only.

About BUB1B / BubR1

O60566 NM_001211 NP_001202.4

BUB1B Antibody, Bub1A Antibody, BUBR1 Antibody, HBUBR1 Antibody, Protein SSK1 Antibody, SSK1 Antibody, BUB1beta Antibody, MAD3L Antibody

Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE.

Western blot

Western blot
Western blot of ubR1 (T368) pAb in extracts from HeLa cells treated with H2O2 100uM 30'.

Requested From: 
Date Requested: 12/14/2017

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