Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone AV20] (IgG1) to Chicken Bu-1
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Chicken (tested or 100% immunogen sequence identity)
Turkey, Guinea fowl, Quail
IgG1 Monoclonal [AV20]
Ion exchange chromatography
IHC - Frozen
Specificity and Use
Bu-1 antibody was raised against bursal cells from day old H. B15 (Bu-1a/b) chickens.
Recognizes Chicken Bu-1a/b, also known as ChL6, a type 1 transmembrane protein. Bu-1 is a product of two alleles, Bu-1a ad Bu-1b, clone AV20 recognizes both alleles. The Bu-1 antigen is expressed by chicken B-cells throughout most of their development and by a subset of monocytes and macrophages. The antigen is absent from erythrocytes, granulocytes and thrombocytes. Clone AV20 does not cross react with Turkey (Meleagris gallopavo), Guinea fowl (Numida meleagris) or Japanese quail (Coturnix coturnix japonica).
Borate buffered saline, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.