BTRCP / BETA-TRCP

beta-transducin repeat containing E3 ubiquitin protein ligase

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds to phosphorylated target proteins. SCF(BTRC) mediates the ubiquitination of CTNNB1 and participates in Wnt signaling. SCF(BTRC) mediates the ubiquitination of NFKBIA, NFKBIB and NFKBIE; the degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. Ubiquitination of NFKBIA occurs at 'Lys-21' and 'Lys-22'. SCF(BTRC) mediates the ubiquitination of phosphorylated NFKB1/nuclear factor NF-kappa-B p105 subunit, ATF4, CDC25A, DLG1, FBXO5, PER1, SMAD3, SMAD4, SNAI1 and probably NFKB2. Has an essential role in the control of the clock-dependent transcription via degradation of phosphorylated PER1 and PER2. May be involved in ubiquitination and subsequent proteasomal degradation through a DBB1-CUL4 E3 ubiquitin-protein ligase. Required for activation of NFKB-mediated transcription by IL1B, MAP3K14, MAP3K1, IKBKB and TNF. Required for proteolytic processing of GLI3.

☰ Filters

Products

Antibodies (45)

Proteins (1)

Type

Primary (45)

Recombinant (1)

Target

BTRCP / BETA-TRCP (46)

Reactivity

Human (43)

Mouse (12)

Rat (12)

Bovine (6)

Chimpanzee (3)

Dog (6)

Gibbon (6)

Guinea pig (3)

Horse (3)

Monkey (6)

Orangutan (3)

Pig (6)

Rabbit (6)

Xenopus (3)

more less

Application

IHC (15)

IHC-P (3)

WB (42)

Flo (5)

ELISA (15)

FLISA (3)

ICC (5)

IF (16)

IP (6)

Peptide-ELISA (1)

Host

rabbit (25)

mouse (20)

Product Group

IHCPlus (2)

Isotype

IgG (13)

IgG1 (12)

IgG1,k (6)

IgG2b (2)

Clonality

monoclonal mc (20)

polyclonal pc (25)

Clone

3D5E6 (1)

4C5D8 (1)

OTI1A4 (2)

OTI1D4 (2)

OTI1F10 (2)

OTI1F3 (2)

OTI2H2 (2)

OTI3D5 (2)

Format

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (5)

Carrier-free (6)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (2)

Unconjugated (26)

Epitope

aa52-354 (8)

aa17-52 (7)

C-Terminus (4)

aa49-98 (4)

aa127-156 (1)

Publications

No (46)

Tag

GST (1)

Species

Human (1)

Source

Wheat Germ Extract (1)

Purification

Purified (1)

Select

BTRCP / BETA-TRCP Antibody LS-C331612

Antibody:

BTRCP / BETA-TRCP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

BTRCP / BETA-TRCP Antibody (C-Terminus) LS-C145640

Antibody:

BTRCP / BETA-TRCP Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

BTRCP / BETA-TRCP Antibody (C-Terminus, HRP) LS-C443302

Antibody:

BTRCP / BETA-TRCP Rabbit anti-Mouse Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP

• Unconjugated
• HRP

Select

BTRCP / BETA-TRCP Antibody (clone OTI2H2) LS-C172699

Antibody:

BTRCP / BETA-TRCP Mouse anti-Human Monoclonal (OTI2H2) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

BTRCP / BETA-TRCP Antibody (aa52-354, clone OTI2H2, Carrier-free) LS-C785672

Antibody:

BTRCP / BETA-TRCP Mouse anti-Human Monoclonal (aa52-354) (Carrier-free) (OTI2H2) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

BTRCP / BETA-TRCP Antibody (aa49-98) LS-B14010

Antibody:

BTRCP / BETA-TRCP Rabbit anti-Rat Polyclonal (aa49-98) Antibody

Reactivity:

Rat

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

Select

IHC-plus™ BTRCP / BETA-TRCP Antibody LS-B14579

(4.0) Rating

Antibody:

BTRCP / BETA-TRCP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

BTRCP / BETA-TRCP Antibody LS-C39733

Antibody:

BTRCP / BETA-TRCP Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$737

Select

BTRCP / BETA-TRCP Antibody (clone 4C5D8) LS-C682511

Antibody:

BTRCP / BETA-TRCP Mouse anti-Human Monoclonal (4C5D8) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

BTRCP / BETA-TRCP Antibody LS-C502254

Antibody:

BTRCP / BETA-TRCP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

BTRCP / BETA-TRCP Antibody (aa17-52) LS-C156893

Antibody:

BTRCP / BETA-TRCP Rabbit anti-Human Polyclonal (aa17-52) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

BTRCP / BETA-TRCP Antibody (aa17-52) LS-C319909

Antibody:

BTRCP / BETA-TRCP Rabbit anti-Human Polyclonal (aa17-52) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

BTRCP / BETA-TRCP Antibody (aa17-52, Biotin) LS-C212987

Antibody:

BTRCP / BETA-TRCP Rabbit anti-Human Polyclonal (aa17-52) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

BTRCP / BETA-TRCP Antibody (aa17-52, FITC) LS-C212988

Antibody:

BTRCP / BETA-TRCP Rabbit anti-Human Polyclonal (aa17-52) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

BTRCP / BETA-TRCP Antibody (aa17-52, APC) LS-C212986

Antibody:

BTRCP / BETA-TRCP Rabbit anti-Human Polyclonal (aa17-52) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

BTRCP / BETA-TRCP Antibody (aa17-52, PE) LS-C212992

Antibody:

BTRCP / BETA-TRCP Rabbit anti-Human Polyclonal (aa17-52) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

BTRCP / BETA-TRCP Antibody (aa17-52, Azide-free, HRP) LS-C212989

Antibody:

BTRCP / BETA-TRCP Rabbit anti-Human Polyclonal (aa17-52) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

BTRCP / BETA-TRCP Antibody LS-C809543

Antibody:

BTRCP / BETA-TRCP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

BTRCP / BETA-TRCP Antibody (clone 3D5E6) LS-C682528

Antibody:

BTRCP / BETA-TRCP Mouse anti-Human Monoclonal (3D5E6) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

Human BTRCP / BETA-TRCP Protein (Recombinant GST) (Full Length) - LS-G31412

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

95.3 kDa

Price:

2 µg/$439

Select

BTRCP / BETA-TRCP Antibody (aa52-354, clone OTI3D5) LS-C337269

Antibody:

BTRCP / BETA-TRCP Mouse anti-Human Monoclonal (aa52-354) (OTI3D5) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

BTRCP / BETA-TRCP Antibody (aa52-354, clone OTI3D5, Carrier-free) LS-C785673

Antibody:

BTRCP / BETA-TRCP Mouse anti-Human Monoclonal (aa52-354) (Carrier-free) (OTI3D5) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

BTRCP / BETA-TRCP Antibody (aa52-354, clone OTI1A4) LS-C337278

Antibody:

BTRCP / BETA-TRCP Mouse anti-Human Monoclonal (aa52-354) (OTI1A4) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

BTRCP / BETA-TRCP Antibody (aa52-354, clone OTI1A4, Carrier-free) LS-C785728

Antibody:

BTRCP / BETA-TRCP Mouse anti-Human Monoclonal (aa52-354) (Carrier-free) (OTI1A4) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

BTRCP / BETA-TRCP Antibody (clone OTI1F10) LS-C172698

Antibody:

BTRCP / BETA-TRCP Mouse anti-Human Monoclonal (OTI1F10) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

100 µl/$434

Viewing 1-25 of 46 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.