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BSN / Bassoon
bassoon presynaptic cytomatrix protein
Neurotransmitters are released from a specific site in the axon terminal called the active zone, which is composed of synaptic vesicles and a meshwork of cytoskeleton underlying the plasma membrane. The protein encoded by this gene is thought to be a scaffolding protein involved in organizing the presynaptic cytoskeleton. The gene is expressed primarily in neurons in the brain. A similar gene product in rodents is concentrated in the active zone of axon terminals and tightly associated with cytoskeletal structures, and is essential for regulating neurotransmitter release from a subset of synapses.
| Gene Name: | bassoon presynaptic cytomatrix protein |
| Synonyms: | BSN, Bassoon, Zinc finger protein 231, Protein bassoon, KIAA0434, ZNF231 |
| Target Sequences: | NM_003458 NP_003449.2 Q9UPA5 |
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