Human BRCA1

Rabbit

Human, Mouse, Rat (tested or 100% immunogen sequence identity)

Polyclonal

Unconjugated

Protein G purified

Unmodified

KLH-conjugated synthetic peptide from the N-Terminus of human BRCA1.

Breast cancer type 1 susceptibility protein (BRCA1) plays a central role in DNA repair by facilitating cellular response to DNA repair. BRCA1 is required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. BRCA1 is part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex. Defects in BRCA1 are a cause of genetic susceptibility to breast and ovarian cancers.

• Western blot (1:100 - 1:500)
• ELISA (1:500 - 1:1000)

PBS, pH 7.4, 0.09% sodium azide, 12.5% glycerol.

Store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P38398 NCBI: NM_007294 NP_009225.1