LSBio The Immunohistochemistry Antibody Company
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Sandwich ELISA Kits
  • Competitive EIA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Direct ELISA Kits
  • Functional ELISA Kits
  • Phospho-Specific ELISA Kits
  • Custom ELISA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Other
  • Blocking Peptides
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question?
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Publications
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Contact Us

2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products. - To submit a new order. - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues. - To request technical information requests about an LSBio product or its application. - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-BRCA1 Antibody (aa762-1315) LS-C83427


Wt. Vol. Conc. Price
- 100 µl 1 mg/ml $415
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular BRCA1 Antibodies

Anti-BRCA1 Antibody (C-Terminus, clone GLK-2) LS-C95602
Mouse Monoclonal [clone GLK-2] (IgM) to Human BRCA1
IHC - Paraffin
Anti-BRCA1 Antibody IHC-plus™ LS-B3772
Rabbit Polyclonal to Human BRCA1
Human, Mouse, Rat
IHC - Paraffin, Western blot, Immunoprecipitation
Immunohistochemistry Image
Anti-BRCA1 Antibody (HRP) LS-C210784
Rabbit Polyclonal (IgG) to Human BRCA1
Western blot, ELISA
HRP Conjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1) to Human BRCA1
IHC, Western blot, Immunoprecipitation


Human BRCA1
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Protein G purified


  • IHC (1 - 10 µg/ml)
  • Western blot (1 - 10 µg/ml)
  • Immunoprecipitation (1 - 10 µg/ml)

Specificity and Use

BRCA1 antibody was raised against gST fusion protein expressed in E. coli corresponding to aa 762-1315 of full-length BRCA1.
Recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein, and does not recognize the ~exon 11 splice variant. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cytoplasm. Its usefulness to monitor functional inactivation of BRCA1 in sporadic breast cancers is under active investigation.


PBS, pH 7.4
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About BRCA1

P38398 NM_007294 NP_009225.1

BRCA1 Antibody, BROVCA1 Antibody, BRCC1 Antibody, Breast cancer 1, early onset Antibody, PPP1R53 Antibody, PSCP Antibody, PNCA4 Antibody, RING finger protein 53 Antibody, RNF53 Antibody, BRCAI Antibody, Breast cancer 1 early onset Antibody, IRIS Antibody

E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function.

Requested From: United States
Date Requested: 10/21/2016

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn
Copyright © 2016 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number