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Catalog Number Size Price
LS-C83426-100 100 µg $563 
Antibody

Monoclonal Mouse anti‑Human BRCA1 Antibody (aa341‑748, WB) LS‑C83426

Monoclonal Mouse anti‑Human BRCA1 Antibody (aa341‑748, WB) LS‑C83426

Antibody:
BRCA1 Mouse anti-Human Monoclonal (aa341-748) Antibody
Application:
WB, IP
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$563
LS-C83426-100
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
BRCA1 Mouse anti-Human Monoclonal (aa341-748) Antibody
Application:
WB, IP
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
BRCA1 antibody LS-C83426 is an unconjugated mouse monoclonal antibody to human BRCA1 (aa341-748). Validated for IP and WB.
Target
Human BRCA1
Synonyms
BRCA1 | BROVCA1 | BRCC1 | Breast cancer 1, early onset | PPP1R53 | PSCP | PNCA4 | RING finger protein 53 | RNF53 | BRCAI | Breast cancer 1 early onset | IRIS
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
GST fusion protein expressed in E. coli corresponding to aa 341-748 of full-length BRCA1.
Epitope
aa341-748
Specificity
Recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cytoplasm. Its usefulness to monitor functional inactivation of BRCA1 in sporadic breast cancers is under active investigation.
Applications
  • Western blot
  • Immunoprecipitation (1 - 10 µg/ml)
Presentation
PBS, pH 7.4
Storage
Store at -70°C, avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About BRCA1
P38398 NM_007294 NP_009225.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/19/2024