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BRAP2

BRCA1 associated protein

Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.

Gene Name: BRCA1 associated protein
Synonyms: BRAP, BRAP2, IMP, Galectin-2-binding protein, RING finger protein 52, RNF52, BRCA1 associated protein, BRCA1-associated protein
Target Sequences: NM_006768 NP_006759.3 Q7Z569

☰ Filters
Antibodies (25)
Proteins (4)
Over-Expression Lysate (2)
Primary (25)
Recombinant (2)
BRAP2 (29)
Human (25)
Mouse (3)
Bat (3)
Bovine (3)
Chicken (3)
Chimpanzee (3)
Dog (3)
Hamster (3)
Horse (3)
Monkey (4)
IHC (2)
IHC-P (4)
WB (16)
Flo (4)
ELISA (11)
IF (6)
IP (2)
Peptide-ELISA (1)
rabbit (19)
mouse (6)
Product Group
IHCPlus (1)
IgG (13)
IgG1 (5)
monoclonal mc (6)
polyclonal pc (19)
BRCA1/1398 (2)
BRCA1/1472 (2)
APC Conjugated (1)
Azide-free (3)
Biotin Conjugated (3)
BSA-free (2)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (14)
aa66-95 (7)
C-Terminus (4)
aa510-560 (1)
aa560-592 (1)
aa67-79 (1)
No (29)
His (1)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Yeast (1)
BRAP2 Antibody - Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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BRAP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
BRAP2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
BRAP2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
BRAP2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
BRAP2 Antibody - Anti-BRAP antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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BRAP2 Rabbit anti-Human Polyclonal (aa67-79) Antibody
Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
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BRAP2 Mouse anti-Human Monoclonal (BRCA1/1472) Antibody
Human
ELISA, Flo, IF
Unconjugated
20 µg/$371; 100 µg/$574
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BRAP2 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (BRCA1/1472) Antibody
Human
ELISA, Flo, IF
Unconjugated, Azide-free, BSA-free
100 µg/$574
BRAP2 Antibody - IHC testing of FFPE human breast carcinoma tissue with BRCA1 antibody (clone BRCA1/1398). HIER: boil tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min.
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BRAP2 Mouse anti-Human Monoclonal (BRCA1/1398) Antibody
Human
Flo, IF, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
BRAP2 Antibody - IHC testing of FFPE human breast carcinoma tissue with BRCA1 antibody (clone BRCA1/1398). HIER: boil tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min.
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BRAP2 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (BRCA1/1398) Antibody
Human
Flo, IF, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
BRAP2 Antibody - Western blot analysis of BRAP using LOVO cells whole cells lysates
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BRAP2 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
BRAP2 Antibody - Western blot analysis of extracts from CHO-K1 cells, transfected with a human pFLAG-CMV2-BRAP construct (A) or transfected with a human pFLAG-CMV2 construct (B) , using BRAP mouse mAb (1:1000 diluted).
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BRAP2 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
Select
BRAP2 Rabbit anti-Human Polyclonal (aa66-95) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
BRAP2 Rabbit anti-Human Polyclonal (aa66-95) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
BRAP2 Rabbit anti-Human Polyclonal (aa66-95) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
BRAP2 Rabbit anti-Human Polyclonal (aa66-95) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
BRAP2 Rabbit anti-Human Polyclonal (aa66-95) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
BRAP2 Rabbit anti-Human Polyclonal (aa66-95) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
BRAP2 Rabbit anti-Human Polyclonal (aa560-592) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
BRAP2 Antibody - Western blot analysis of extracts from CHO-K1 cells, transfected with a human pFLAG-CMV2-BRAP construct (A) or transfected with a human pFLAG-CMV2 construct (B), using BRAP mouse monoclonal antibody (1:1000 dilution).
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BRAP2 Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$391
BRAP2 Antibody - BRAP antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
BRAP2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
BRAP2 Antibody - BRAP antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
BRAP2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Chicken, Bovine, Mouse, Dog, Hamster, Horse, Bat, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
BRAP2 Antibody - BRAP antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
BRAP2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Chicken, Bovine, Mouse, Dog, Hamster, Horse, Bat, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
BRAP2 Antibody - BRAP antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
BRAP2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Chicken, Bovine, Mouse, Dog, Hamster, Horse, Bat, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
BRAP2 Antibody - BRAP Antibody western blot of 293 cell line lysates (35 ug/lane). The BRAP antibody detected the BRAP protein (arrow).
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BRAP2 Rabbit anti-Human Polyclonal (aa66-95) Antibody
Human
WB
Unconjugated
400 µl/$393
Select
BRAP2 Rabbit anti-Human Polyclonal (aa510-560) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
Viewing 1-25 of 29 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).