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BPIFA1 / SPLUNC1

BPI fold containing family A, member 1

Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Binds bacterial lipopolysaccharide (LPS). Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants. May attract macrophages and neutrophils. May be associated with tumor progression.

Gene Name: BPI fold containing family A, member 1
Synonyms: BPIFA1, BA49G10.5, Lung-specific protein X, LUNX, Ligand-binding protein RYA3, SPLUNC1, SPURT, Von Ebner protein Hl, LPLUNC3, NASG, PLUNC, Protein Plunc
Target Sequences: NM_016583 NP_057667.1 Q9NP55

Publications (1)

1
Increased expression of BPI fold-containing family A member 1 is associated with metastasis and poor prognosis in human colorectal carcinoma. Wang H, Jiang D, Li W, Wang S. Oncology letters. 2017 October;14:4231-4236. (Human) [Full Text Article] [PubMed:28943932] [PMC:PMC5604161] Related Antibodies: LS-B3549.

☰ Filters
Antibodies (21)
Proteins (10)
ELISA Kits (3)
Over-Expression Lysate (4)
Primary (21)
Recombinant (6)
Sandwich (3)
BPIFA1 / SPLUNC1 (34)
Human (21)
Mouse (6)
Rat (8)
Bat (3)
Bovine (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Monkey (3)
Pig (3)
IHC (6)
IHC-P (4)
WB (20)
ELISA (2)
Peptide-ELISA (3)
rabbit (19)
goat (2)
Product Group
IHCPlus (1)
IgG (9)
polyclonal pc (21)
96-Well Microplate (1)
96-Well Strip Plate (2)
APC (1)
APC Conjugated (1)
Biotin Conjugated (2)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (11)
aa20-256 (8)
aa101-150 (4)
Internal (2)
aa167-180 (1)
aa228-241 (1)
No (33)
Yes (1)
Cell Culture Supernatants (1)
Cell Lysates (1)
Plasma (3)
Serum (3)
Tissue Homogenates (2)
6His-SUMO, N-terminus (1)
GST (1)
His (1)
His-GST (1)
Myc-DDK (Flag) (6)
Human (8)
293T Cells (2)
E. coli (3)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Purified (3)
BPIFA1 / SPLUNC1 Antibody - Anti-PLUNC antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal (aa101-150) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
BPIFA1 / SPLUNC1 Antibody - Anti-PLUNC antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal (aa101-150) (HRP) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Bat, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
BPIFA1 / SPLUNC1 Antibody - Anti-PLUNC antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal (aa101-150) (Biotin) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Bat, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
BPIFA1 / SPLUNC1 Antibody - Anti-PLUNC antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal (aa101-150) (FITC) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Bat, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
BPIFA1 / SPLUNC1 ELISA Kit
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Sandwich
96-Well Microplate
Human
40 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$672
BPIFA1 / SPLUNC1 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
BPIFA1 / SPLUNC1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$834
BPIFA1 / SPLUNC1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$854
BPIFA1 / SPLUNC1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
24.6 kDa
20 µg/$150
BPIFA1 / SPLUNC1 Protein - Recombinant  Palate/Lung And Nasal Epithelium Associated Protein By SDS-PAGE
Select
E. coli
His-GST
54.6 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
BPIFA1 / SPLUNC1 Antibody - 1:100 staining human lung carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$386
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BPIFA1 / SPLUNC1 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
BPIFA1 / SPLUNC1 Antibody - BPIFA1 antibody (2 ug/ml) staining of secretions from Human primary airway cells in culture (lanes 1 and 2), and in Human Bronchoalveolar Lavage fluid (lanes 3 and 4) . Data obtained from Dr. C Bingle, AURM, University of Sheffield, UK. Primary incubation was 1 hour. Detected by chemiluminescence.
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BPIFA1 / SPLUNC1 Goat anti-Human Polyclonal (aa228-241) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
BPIFA1 / SPLUNC1 Antibody - Goat Anti-BPIFA1 / PLUNC Antibody (2µg/ml) staining of secretions from Human primary airway cells in culture (lanes 1 and 2), and in Human Bronchoalveolar Lavage fluid (lanes 3 and 4) . Data obtained from Dr. C Bingle, AURM, University of Sheffield, UK. Primary incubation was 1 hour. Detected by chemiluminescencence.
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BPIFA1 / SPLUNC1 Goat anti-Human Polyclonal (aa167-180) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
BPIFA1 / SPLUNC1 Antibody - Western blot of BPIFA1 / SPLUNC1 antibody.
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal (aa20-256) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
BPIFA1 / SPLUNC1 Antibody - Western blot of BPIFA1 / SPLUNC1 antibody.
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal (aa20-256) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
BPIFA1 / SPLUNC1 Antibody - Western blot of BPIFA1 / SPLUNC1 antibody.
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal (aa20-256) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
BPIFA1 / SPLUNC1 Antibody - Western blot of BPIFA1 / SPLUNC1 antibody.
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal (aa20-256) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
BPIFA1 / SPLUNC1 Antibody - Western blot of BPIFA1 / SPLUNC1 antibody.
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal (aa20-256) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
BPIFA1 / SPLUNC1 Antibody - Western blot of BPIFA1 / SPLUNC1 antibody.
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal (aa20-256) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
BPIFA1 / SPLUNC1 Antibody - Western blot of BPIFA1 antibody at 1:500 dilution. Lane 1: A549 whole cell lysate. Lane 2: PC12 whole cell lysate.
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
BPIFA1 / SPLUNC1 Antibody - Western blot analysis of PLUNC expression in A549 (A); PC12 (B) whole cell lysates.
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BPIFA1 / SPLUNC1 Rabbit anti-Human Polyclonal (Internal) Antibody
Rat, Human
WB
Unconjugated
100 µl/$299
Viewing 1-25 of 34 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).