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immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
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Botulinum Neurotoxin type B antibody LS-C79422 is an unconjugated mouse monoclonal antibody to clostridium botulinum Botulinum Neurotoxin type B. Validated for ELISA, Func, ICC, IF and RIA.
Clostridium botulinum Botulinum Neurotoxin type B
(tested or 100% immunogen sequence identity)
Tissue culture supernatant
Synthetic peptide analogue of the carboxyl terminal region of C. botulinum Toxin B.
Recognizes and binds to intact whole C. botulinum Toxin B, amino acids 1278-1291. Has been found to stain Neuro2A cells treated with GT1b ganglioside prior to the addition of C. botulinum Toxin B. Inhibits the entry of C. botulinum Toxin B to Neuro2A cells treated with GT1b ganglioside prior to the addition of the toxin. Cross-reactivity: C. botulinum Toxin B (1278-1291): 100% C. botulinum Toxin B: 100%, C. botulinum Toxin A, C, E and F (1272-1280): 0%.
Suitable for use in ELISA, Immunofluorescence, Indirect Immunocytochemistry and RIA. Indirect Immunocytochemistry:1:25. Note: Prior incubation of the antibody with synthetic peptide immunogen has been shown to eliminate the inhibition of cellular binding by the antibody.