Clostridium botulinum Botulinum Neurotoxin type B
(tested or 100% immunogen sequence identity)
Tissue culture supernatant
- ICC (1:25)
- Functional Assay
Synthetic peptide analogue of the carboxyl terminal region of C. botulinum Toxin B.
Recognizes and binds to intact whole C. botulinum Toxin B, amino acids 1278-1291. Has been found to stain Neuro2A cells treated with GT1b ganglioside prior to the addition of C. botulinum Toxin B. Inhibits the entry of C. botulinum Toxin B to Neuro2A cells treated with GT1b ganglioside prior to the addition of the toxin. Cross-reactivity: C. botulinum Toxin B (1278-1291): 100% C. botulinum Toxin B: 100%, C. botulinum Toxin A, C, E and F (1272-1280): 0%.
Suitable for use in ELISA, Immunofluorescence, Indirect Immunocytochemistry and RIA. Indirect Immunocytochemistry:1:25. Note: Prior incubation of the antibody with synthetic peptide immunogen has been shown to eliminate the inhibition of cellular binding by the antibody.
No preservatives added
For research use only.