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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Botulinum Neurotoxin Type A Antibody (aa1280‑1292) LS‑C79418
Antibody
Botulinum Neurotoxin Type A antibody LS-C79418 is an unconjugated mouse monoclonal antibody to clostridium botulinum Botulinum Neurotoxin Type A. Validated for ELISA, Func, ICC, IF and RIA.
Catalog
Size
Price
LS-C79418-500
500 µl
Unavailable

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Product Description

Botulinum Neurotoxin Type A antibody LS-C79418 is an unconjugated mouse monoclonal antibody to clostridium botulinum Botulinum Neurotoxin Type A. Validated for ELISA, Func, ICC, IF and RIA.

Specifications

Target
Clostridium botulinum Botulinum Neurotoxin Type A
Host
Mouse
Reactivity
Clostridium botulinum (tested or 100% immunogen sequence identity)
Clonality
IgM Monoclonal
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Unmodified
Applications
  • ICC (1:25)
  • Immunofluorescence
  • ELISA
  • Functional Assay
  • Radioimmunoassay
Immunogen
Synthetic peptide analogue of the carboxyl terminal region of C. botulinum Toxin A.
Epitope
aa1280-1292
Specificity
Recognizes and binds to intact whole C. botulinum Toxin A, amino acids 1280-1292. Has been found to stain Neuro2A cells treated with GT1b ganglioside prior to the addition of C. botulinum Toxin A. Inhibits the entry of C. botulinum Toxin A to Neuro2A cells treated with GT1b ganglioside prior to the addition of the toxin. Cross-reactivity: C. botulinum Toxin A (1280-1292): 100%, C. botulinum Toxin A: 100%C. botulinum Toxin B, C, E and F (1272-1280): 0%.
Usage
Suitable for use in ELISA, Immunofluorescence, Indirect Immunocytochemistry and RIA. Immunocytochemistry (Indirect): 1:12.5. Note: Prior incubation of the antibody with synthetic peptide immunogen has been shown to eliminate the inhibition of cellular binding by the antibody.
Presentation
PBS, 40% glycerol. No preservatives added.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/22/2018

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