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Anti-BMP6 Antibody (clone morph-6.1, Biotin) LS-C96419


Wt. Vol. Conc. Price
100 µg - - Unavailable

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100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone morph-6.1]
IHC - Frozen
Biotin Conjugated


Rat (tested or 100% immunogen sequence identity)
Monoclonal [morph-6.1]
Affinity purified


IHC - Frozen (1:100 - 1:200)

Specificity and Use

BMP6 antibody was raised against aminoterminal synthetic peptide 1-29-KLh
Bone morphogenic protein 6. Pre-incubation of morph-6.1 with amino-terminal peptide 1-29 of BMP-6 inhibits binding of the antibody to tissue sections. Pre-incubation with other amino- terminal synthetic peptides of human BMP-7, BMP-4, BMP-3 and BMP-2 as well as an irrelevant peptide does not inhibit specific tissue staining. Antigen distribution: Tissue sections: Positive staining can be observed in embryonic and adult central nervous system. Rat radial glial cells of the developing central nervous system from E11 to E19. In rat peripheral nerves a selective intracellular immunoreactivity can be found in perinuclear region of most Schwann cells which form the myelin sheath. However, some Schwann cells were negative for morph-6.1. BMP-6 can also be found in a variety of other tissues and cell types, notably keratinizing epithelial cells. Smooth muscle cells, characterized by Desmin positivity, were positively stained in normal tissues and in atherosclerotic plaques. Macrophages (CD68+) and endothelial cells were negative with morph-6.1. Specificity: Rat: Bone morphogenic Protein-6 (BMP-6) Synonyms are: vgr-1 (vegetal related) or DVR-6 (decapentaplegic vegetal related). Other species: phylogenetically highly conserved (human positive)
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.


Lyophilized from PBS pH 7.2, 5mg/ml BSA, 0.09%sodium azide
0.5ml distilled water
Store at 4°C.
For research use only.

About BMP6

P22004 NM_001718 NP_001709.1

BMP6 Antibody, BMP-6 Antibody, Bone morphogenetic protein 6 Antibody, VG-1-related protein Antibody, VGR1 Antibody, VG-1-R Antibody, VGR Antibody, Vg1 Antibody, Vg1-related sequence Antibody, VGR-1 Antibody

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development.

Requested From: 
Date Requested: 4/23/2017

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