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BMP6

bone morphogenetic protein 6

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

Gene Name: bone morphogenetic protein 6
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: BMP6, BMP-6, Bone morphogenetic protein 6, VG-1-related protein, VGR1, VG-1-R, VGR, Vg1, Vg1-related sequence, VGR-1
Target Sequences: NM_001718 NP_001709.1 P22004

Publications (2)

1
KLF4 is a key determinant in the development and progression of cerebral cavernous malformations. Cuttano R, Rudini N, Bravi L, Corada M, Giampietro C, Papa E, Morini MF, Maddaluno L, Baeyens N, Adams RH, Jain MK, Owens GK, Schwartz M, Lampugnani MG, Dejana E. EMBO molecular medicine. 2016 8:6-24. (IHC; Mouse) [Full Text Article] [PubMed:26612856] [PMC:PMC4718159]
2
Lysosomal exocytosis of HSP70 stimulates monocytic BMP6 expression in Sjögren's syndrome. Ying-Qian Mo, Hiroyuki Nakamura, Tsutomu Tanaka, Toshio Odani, Paola Perez, Youngmi Ji, Benjamin N French, Thomas Jf Pranzatelli, Drew G Michael, Hongen Yin, Susan S Chow, Maryam Khalaj, Sandra A Afione, Changyu Zheng, Fabiola Reis Oliveira, Ana Carolina F Motta, Alfredo Ribeiro-Silva, Eduardo M Rocha, Cuong Q Nguyen, Masayuki Noguchi, Tatsuya Atsumi, Blake M Warner, John A Chiorini. The Journal of clinical investigation. 2022 February;132:e152780. [Full Text Article] [PubMed:35113815] [PMC:PMC8920330]

☰ Filters
Antibodies (56)
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BMP6 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$772
BMP6 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
BMP6 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$782
BMP6 Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using BMP6 Polyclonal Antibody at dilution of 1:50.
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BMP6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
BMP6 Antibody - Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Bmp6 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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BMP6 Rabbit anti-Human Polyclonal (aa25-55) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
BMP6 Antibody - Western blot of recombinant BMP6 / BMP-6.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP6 Rabbit anti-Human Polyclonal (aa375-513) Antibody
Rat, Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
BMP6 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$887
BMP6 Protein - Recombinant Bone Morphogenetic Protein 6 By SDS-PAGE
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E. coli
His, N-Terminal
15.9 kDa
10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252
BMP6 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Neuroscience
BMP6 Rabbit anti-Human Polyclonal (aa359-408) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
BMP6 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP6 Rabbit anti-Human Polyclonal (aa359-408) (FITC) Antibody
Rabbit, Mouse, Goat, Dog, Guinea pig, Sheep, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
BMP6 Antibody - Anti-BMP6 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Neuroscience
BMP6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
BMP6 Antibody - Anti-BMP6 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP6 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
BMP6 Antibody - Anti-BMP6 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP6 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
BMP6 Antibody - Anti-BMP6 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP6 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
BMP6 Antibody
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BMP6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$575
BMP6 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Neuroscience
BMP6 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P, WB
Unconjugated
50 µg/$460
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BMP6 Rabbit anti-Human Polyclonal (aa25-55) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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BMP6 Rabbit anti-Human Polyclonal (aa25-55) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
200 µl/$952
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BMP6 Rabbit anti-Human Polyclonal (aa25-55) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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BMP6 Rabbit anti-Human Polyclonal (aa25-55) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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BMP6 Rabbit anti-Human Polyclonal (aa25-55) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
BMP6 Antibody - IHC of BMP-6 (A152) pAb in paraffin-embedded human lung carcinoma tissue.
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BMP6 Rabbit anti-Human Polyclonal (Ala152) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$391
BMP6 Antibody - Immunohistochemistry analysis of BMP-6 antibody in paraffin-embedded human lung carcinoma tissue.
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BMP6 Rabbit anti-Human Polyclonal (aa103-152) Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
BMP6 Antibody - 1:100 staining human brain tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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BMP6 Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
BMP6 Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using BMP6 Polyclonal Antibody at dilution of 1:40.
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BMP6 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Viewing 1-25 of 95 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).