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Anti-BMP10 Antibody (aa314-421, clone 11n14) LS-C184179

Ordering

Wt. Vol. Conc. Price
100 µg 200 µl - $530
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular BMP10 Antibodies

Anti-BMP10 Antibody (aa22-35) IHC-plus™ LS-B202
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Immunohistochemistry Image
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Anti-BMP10 Antibody (aa84-94) LS-C127072
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100% Guaranteed 100% Guaranteed
Rat Monoclonal [clone 11n14] (IgG2a) to Human BMP10
Human
IHC
Unconjugated

Details

Human BMP10
Rat
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [11n14]
Unconjugated
Protein A/G purified
Unmodified

Applications

IHC (8 - 25 µg/ml)

Specificity and Use

BMP10 antibody was raised against recombinant corresponding to aa314-421 from human BMP-10 expressed in CHO cells (Q9R229).
aa314-421
Mouse BMP-10. Species sequence homology: recombinant human BMP-10, rhBMP-8a (10%), recombinant mouse BMP-8b. Does not react with rmBMP-3, -4, -5, -6, -7, -9, -15, rhBMP-1.1, -2, -3b, propeptide rhBMP-10.

Packaging

Lyophilized from PBS, trehalose
200 µl Sterile PBS
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C.
For research use only.

About BMP10

O95393 NM_014482 NP_055297.1

BMP10 Antibody, BMP-10 Antibody, Bone morphogenetic protein 10 Antibody

Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth.

Requested From: United States
Date Requested: 12/4/2016

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