BLNK

B-cell linker

Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca2+ mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.

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Products

Antibodies (74)

ELISA Kits (13)

Proteins (12)

Type

Cell-Based (1)

Cell-Based Phosphorylation (2)

Custom (4)

Over-Expression Lysate (4)

Primary (74)

Recombinant (8)

Sandwich (6)

Target

BLNK (99)

Reactivity

Human (77)

Mouse (41)

Rat (15)

Bat (4)

Bovine (5)

Chicken (2)

Dog (4)

Gibbon (3)

Guinea pig (4)

Hamster (4)

Monkey (7)

Pig (4)

Porcine (1)

Rabbit (4)

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Application

IHC (30)

IHC-P (11)

WB (66)

Flo (4)

ELISA (32)

ICC (2)

IF (7)

IP (1)

Peptide-ELISA (6)

Host

rabbit (59)

mouse (14)

goat (1)

Isotype

IgG (38)

IgG1 (5)

IgG2a,k (6)

IgG2b (2)

IgM (1)

Clonality

monoclonal mc (14)

polyclonal pc (60)

Clone

5G9 (2)

OTI2B2 (2)

OTI4C9 (2)

Polyclonal (1)

Format

96-Well Microplate (3)

96-Well Strip Plate (10)

APC (1)

APC Conjugated (4)

Azide-free (1)

Biotin Conjugated (6)

Carrier-free (2)

Concentrated (1)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (4)

Unconjugated (46)

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Epitope

aa150-178 (8)

aa65-314 (8)

pTyr96 (6)

C-Terminus (4)

aa1-292 (4)

pTyr84 (3)

40-120 aa (2)

aa171-356 (2)

20-100 aa (1)

Asn91 (1)

Internal (1)

aa301-401 (1)

aa394-456 (1)

aa444-456 (1)

aa57-82 (1)

aa62-111 (1)

p96 (1)

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Publications

No (99)

Sample Type

Adherent Cell Cultures (3)

Plasma (1)

Serum (1)

Tag

6His, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

His,C-terminus (1)

His,N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (4)

Species

Human (10)

Source

293T Cells (2)

E. coli (5)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (3)

Select

BLNK Antibody (clone 5G9) LS-C169382

Antibody:

BLNK Mouse anti-Human Monoclonal (5G9) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

BLNK Antibody (C-Terminus) LS-C107723

Antibody:

BLNK Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

BLNK Antibody (clone 5G9) LS-C758947

Antibody:

BLNK Mouse anti-Human Monoclonal (5G9) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$541

Select

BLNK Antibody LS-C812514

Antibody:

BLNK Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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BLNK Antibody LS-C677300

Antibody:

BLNK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

BLNK Antibody (phospho-Tyr96) LS-C801215

Antibody:

BLNK Rabbit anti-Human Polyclonal (pTyr96) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

BLNK Antibody LS-C801659

Antibody:

BLNK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

BLNK Antibody (aa150-178) LS-C99218

Antibody:

BLNK Rabbit anti-Human Polyclonal (aa150-178) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

BLNK Antibody LS-C483771

Antibody:

BLNK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$412

Select

BLNK Antibody (aa1-292, clone OTI4C9) LS-C794399

Antibody:

BLNK Mouse anti-Human Monoclonal (aa1-292) (OTI4C9) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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BLNK Antibody (aa1-292, clone OTI4C9, Carrier-free) LS-C791678

Antibody:

BLNK Mouse anti-Human Monoclonal (aa1-292) (Carrier-free) (OTI4C9) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

BLNK Antibody LS-C830419

Antibody:

BLNK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

BLNK Antibody (aa62-111) LS-C117740

Antibody:

BLNK Rabbit anti-Human Polyclonal (aa62-111) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

BLNK Antibody (phospho-Tyr96) LS-C198688

Antibody:

BLNK Rabbit anti-Human Polyclonal (pTyr96) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

BLNK Antibody (phospho-Tyr84) LS-C198687

Antibody:

BLNK Rabbit anti-Human Polyclonal (pTyr84) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

BLNK Antibody (aa444-456) LS-C20135

Antibody:

BLNK Goat anti-Human Polyclonal (aa444-456) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Hamster, Pig, Bat, Human, Monkey

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

Select

BLNK Antibody (20-100 aa) LS-C381397

Antibody:

BLNK Rabbit anti-Human Polyclonal (20-100 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

BLNK Antibody LS-C659881

Antibody:

BLNK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

BLNK Antibody (40-120 aa) LS-C381276

Antibody:

BLNK Rabbit anti-Human Polyclonal (40-120 aa) Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

BLNK Antibody (40-120 aa) LS-C382285

Antibody:

BLNK Rabbit anti-Human Polyclonal (40-120 aa) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

BLNK Antibody (phospho-Tyr84) LS-C825492

Antibody:

BLNK Rabbit anti-Human Polyclonal (pTyr84) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

BLNK Antibody (phospho-Tyr96) LS-C821987

Antibody:

BLNK Rabbit anti-Human Polyclonal (pTyr96) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

BLNK Antibody (p96) LS-C821990

Antibody:

BLNK Rabbit anti-Human Polyclonal (p96) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

BLNK Antibody (phospho-Tyr96) LS-C413185

Antibody:

BLNK Rabbit anti-Human Polyclonal (pTyr96) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$341

Select

BLNK Antibody (Asn91) LS-C192044

Antibody:

BLNK Rabbit anti-Human Polyclonal (Asn91) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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