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Anti-BLM Antibody LS-C43052

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular BLM Antibodies

Anti-BLM Antibody (aa1319-1335) IHC-plus™ LS-B795
Rabbit Polyclonal to Human BLM
Human
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-BLM Antibody (clone 1E4) LS-C196753
Mouse Monoclonal [clone 1E4] (IgG1,k) to Human BLM
Human
Immunofluorescence, Western blot, ELISA
Unconjugated
Immunofluorescence Image
Anti-BLM Antibody (phospho-Ser144) LS-C209384
Rabbit Polyclonal to Human BLM
Human
Western blot, ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human BLM
Human
Western blot, Immunoprecipitation
Unconjugated

Details

Human BLM
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Affinity purified
Unmodified

Applications

  • Western blot (1:1000 - 1:10000)
  • Immunoprecipitation

Specificity and Use

BLM antibody was raised against synthetic peptide corresponding to a region of human BLM encoded within exon 22.
Recognizes human Bloom Syndrome protein, also known as BLM, RecQ protein-like 3 or DNA helicase, RecQ-like type 2 BLM is a DNA binding protein with helicase activity. BLM is a member of the RecQ family of helicases, which has an important role in maintaining genome stability by suppressing inappropriate recombination. BLM has been implicated in Bloom Syndrome, an autosomal recessive diseases characterized by chromosome fragility and cancer proneness.

Packaging

Tris-citrate/phosphate, 0.09% sodium azide.
For research use only.

About BLM

P54132 NM_000057 NP_000048.1

BLM Antibody, Bloom syndrome Antibody, Bloom syndrome protein Antibody, BS Antibody, Bloom's syndrome protein Antibody, DNA helicase, RecQ-like type 2 Antibody, RECQ2 Antibody, RECQL2 Antibody, RECQL3 Antibody, RecQ protein-like 3 Antibody

Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE).

Western blot

Western blot
Detection of human BLM in whole cell lysates of HeLa and 293T cells as indicated by Western blotting using Rabbit anti-Human BLM (LS-C43052).
 

Requested From: United States
Date Requested: 12/2/2016

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