Human BIRC7 / Livin

Rabbit

Human (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Immunoaffinity purified

Unmodified

aa264-280

Recognizes human Livin, a novel member of the IAP protein family. Livin contains a single baculoviral IAP repeat domain and a RING finger domain and has two isoforms, Livin-a and Livin-~. Transfection of Livin in cells results in protection from apoptosis induced by FADD, Bax, RIP, RIP3, and DR6. Livin interacts directly with caspase-3, -7, and -9 and inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c, and dATP.

• IHC
• Western blot (2 - 4 µg/ml)

Western Blot: 2-4 ug/ml. In immunoblots, a band of 33 kD is detected. A weak band at 30 kD is detected in Raji cell lysate and probably represents the short form of human Livin.

PBS, pH 7.4, 0.02% Sodium Azide

Store at -20°C, stable for 1 year. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q96CA5 NCBI: NM_022161 NP_071444.1