Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling, and cell proliferation, as well as cell invasion and metastasis.
IHC of cIAP1 in formalin-fixed, paraffin-embedded human prostate using LS-C148258 at 1:2000. A, normal prostate. B, prostate intraepithelial neoplasia (PIN). PIN is a premalignant proliferation arising within the prostate. C, prostate cancer. Hematoxylin-Eosin counterstain. Increased cIAP1 expression is PIN and in prostate cancer compared to normal prostate.
Western blot of cIAP1 in human prostate using LS-C148258 at 1:1000. PBH (benign prostate hyperplasia), PIN (prostate intraepithelial neoplasia). Elevated levels of cIAP1 were seen in certain cases of BPH/PIN and prostate cancer compared to normal prostate.