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| Catalog Number | Size | Price |
|---|---|---|
| LS-A797-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human BDKRB2/Bradykinin B2 Receptor Antibody (C‑Terminus, IHC) LS‑A797
PathPlus™ Polyclonal Rabbit anti‑Human BDKRB2/Bradykinin B2 Receptor Antibody (C‑Terminus, IHC) LS‑A797
Antibody:
BDKRB2/Bradykinin B2 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P, ICC
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Overview
Antibody:
BDKRB2/Bradykinin B2 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P, ICC
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Specifications
Description
Bradykinin B2 Receptor (BDKRB2) elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. BDKRB2 associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human BDKRB2/Bradykinin B2 Receptor
Synonyms
BDKRB2 | BK-2 receptor | Bradykinin type-2 receptor | B2R | Bradykinin B2 receptor | BRB2 | BK-2R | BK-2Rs | BK2 | B2 bradykinin receptor | B2bkr | BK-2 | BKR2 | Bradykinin receptor B2
Host
Rabbit
Reactivity
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 18 amino acid peptide from C-Terminus of human BDKRB2 / BK-2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset (94%); Mouse, Pig (83%).
Epitope
C-Terminus
Specificity
Human BDKRB2 / BK-2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except BAHD1 (44%).
Applications
- IHC
- IHC - Paraffin (5 - 10 µg/ml)
- ICC
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About BDKRB2/Bradykinin B2 Receptor
Validation
Heart, Myocardial infarct
Heart, Myocardial infarct
Artery, Tunica media
Artery, Tunica media
Brain Hippocampus Neurons
Brain Hippocampus Neurons
Anti-BDKRB2/Bradykinin B2 Receptor antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BDKRB2/Bradykinin B2 Receptor antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BDKRB2/Bradykinin B2 Receptor antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BDKRB2/Bradykinin B2 Receptor antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Anti-BDKRB2 / BK-2 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with BDKRB2 / BK-2.
Anti-BDKRB2 / BK-2 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with BDKRB2 / BK-2.
Anti-BDKRB2 / BK-2 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Anti-BDKRB2 / BK-2 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
See More About...
LSBio Ratings
PathPlus™ BDKRB2/Bradykinin B2 Receptor Antibody (C-Terminus) for IHC, ICC LS-A797 has an LSBio Rating of
Publications (4.3)
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (4)
Expression of endogenous nuclear bradykinin B2 receptors mediating signaling in immediate early gene activation. Savard M, Barbaz D, Blanger S, Mller-Esterl W, Bkaily G, D'orlans-Juste P, Cot J, Bovenzi V, Gobeil F. Journal of cellular physiology. 2008 216:234-44. (Mouse, Human, Rat)
Immunohistochemical localization of the bradykinin B1 and B2 receptors in human nasal mucosa. Shirasaki H, Kanaizumi E, Himi T. Mediators of inflammation. 2009 2009:102406. (IHC-P; Human)
Structure-activity relationships of novel peptide agonists of the human bradykinin B2 receptor. B[Character e9]langer S, Bovenzi V, C[Character f4]t[Character e9] J, Neugebauer W, Amblard M, Martinez J, Lammek B, Savard M, Gobeil F. Peptides. 2009 Apr;30:777-87.
Targeting intracellular B2 receptors using novel cell-penetrating antagonists to arrest growth and induce apoptosis in human triple-negative breast cancer. Dubuc C, Savard M, Bovenzi V, Lessard A, Fortier A, Côté J, Neugebauer W, Rizzolio F, Geha S, Giordano A, Chemtob S, Gobeil F. Oncotarget. 2018 January;9:9885-9906. (Human)
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Featured Products
Species:
Human
Applications:
Western blot, ELISA
Species:
Human
Applications:
Western blot
Species:
Human, Mouse, Rat
Applications:
Western blot
Species:
Mouse, Rat
Applications:
IHC, Western blot
Species:
Human
Applications:
IHC, Immunofluorescence, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
