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BCL2L14 / BCL-G

BCL2-like 14 (apoptosis facilitator)

Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bcl-G. The mRNA of Bcl-G encodes 2 isoforms, Bcl-GL, which is widely expressed in multiple tissues, and Bcl-GS, which is only found in testis. The Bcl-GS protein is predominantly localized to cytoplasmic organelles whereas Bcl-GL was distributed throughout the cytosol. Overexpression of either protein induced apoptosis, although Bcl-GS was far more potent than Bcl-GS. Apoptosis induction was dependent on the BH3 domain and could be suppressed by co-expression with the anti-apoptotic Bcl-XL protein.

Gene Name: BCL2-like 14 (apoptosis facilitator)
Family/Subfamily: Apoptosis
Synonyms: BCL2L14, Bcl2-L-14, BCLG, BCL-G, Apoptosis regulator Bcl-G
Target Sequences: NM_030766 NP_110393.1 Q9BZR8

Publications (1)

1
A novel role for proline- and acid-rich basic region leucine zipper (PAR bZIP) proteins in the transcriptional regulation of a BH3-only proapoptotic gene. Benito A, Gutierrez O, Pipaon C, Real PJ, Gachon F, Ritchie AE, Fernandez-Luna JL. The Journal of biological chemistry. 2006 281:38351-7. [PubMed:17057225]

☰ Filters
Antibodies (26)
Proteins (13)
Over-Expression Lysate (9)
Primary (26)
Recombinant (4)
BCL2L14 / BCL-G (39)
Human (26)
Mouse (6)
Rat (3)
IHC (9)
IHC-P (2)
WB (23)
ELISA (12)
IF (2)
Peptide-ELISA (1)
rabbit (16)
mouse (10)
Product Group
IHCPlus (1)
IgG (15)
IgG1 (4)
IgG1,k (6)
monoclonal mc (10)
polyclonal pc (16)
OTI2E12 (2)
OTI6D1 (2)
APC Conjugated (2)
Biotin Conjugated (2)
Carrier-free (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (2)
Unconjugated (16)
aa116-216 (4)
C-Terminus (1)
aa1-327 (1)
No (39)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (11)
Human (9)
293T Cells (5)
E. coli (1)
HEK 293 Cells (6)
Wheat Germ Extract (1)
Purified (2)
BCL2L14 / BCL-G Antibody - Anti-BCL2L14 / Bcl G antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2 ug/ml.
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BCL2L14 / BCL-G Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
BCL2L14 / BCL-G Antibody - Immunofluorescence analysis of HeLa cells.
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BCL2L14 / BCL-G Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
BCL2L14 / BCL-G Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-BCL2L14 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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BCL2L14 / BCL-G Mouse anti-Human Monoclonal (aa116-216) (OTI6D1) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
BCL2L14 / BCL-G Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-BCL2L14 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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BCL2L14 / BCL-G Mouse anti-Human Monoclonal (aa116-216) (Carrier-free) (OTI6D1) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
BCL2L14 / BCL-G Antibody - Immunohistochemistry of paraffin-embedded human prostate using antibody at 1:100 dilution.
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BCL2L14 / BCL-G Rabbit anti-Human Polyclonal (aa1-327) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
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BCL2L14 / BCL-G Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
BCL2L14 / BCL-G Antibody - 1:100 staining mouse testis tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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BCL2L14 / BCL-G Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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BCL2L14 / BCL-G Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
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BCL2L14 / BCL-G Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
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BCL2L14 / BCL-G Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
Select
BCL2L14 / BCL-G Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
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BCL2L14 / BCL-G Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
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BCL2L14 / BCL-G Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
BCL2L14 / BCL-G Antibody - Immunohistochemistry of paraffin-embedded Human tonsil using BCL2L14 Polyclonal Antibody at dilution of 1:40.
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BCL2L14 / BCL-G Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
BCL2L14 / BCL-G Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using BCL2L14 Polyclonal Antibody at dilution of 1:40.
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BCL2L14 / BCL-G Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
BCL2L14 / BCL-G Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
BCL2L14 / BCL-G Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY BCL2L14. (Right lane) cDNA for 48 hrs and lysed
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BCL2L14 / BCL-G Mouse anti-Human Monoclonal (aa116-216) (OTI2E12) Antibody
Human
WB
Unconjugated
100 µl/$434
BCL2L14 / BCL-G Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY BCL2L14. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL2L14. (1:2000)
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BCL2L14 / BCL-G Mouse anti-Human Monoclonal (aa116-216) (Carrier-free) (OTI2E12) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
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BCL2L14 / BCL-G Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$649
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BCL2L14 / BCL-G Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
BCL2L14 / BCL-G Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
BCL2L14 / BCL-G Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
Select
BCL2L14 / BCL-G Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
Select
BCL2L14 / BCL-G Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
Select
BCL2L14 / BCL-G Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-25 of 39 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).