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BCL2L13 / Bcl Rambo

BCL2-like 13 (apoptosis facilitator)

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains. A novel, widely expressed member termed Bcl-rambo was recently identified. This protein is localized to mitochondria in mammalian cells and its overexpression induces apoptosis which could be blocked by co-expression of inhibitor of apoptosis proteins (IAPs) such as XIAP, cIAP1, and cIAP2. Bcl-rambo shows overall homology to the anti-apoptotic members containing BH motifs, but unlike Bcl-2, the C-terminal membrane anchor of Bcl-rambo is preceded by a unique 250 amino acid insertion. This region by itself can induce apoptosis more efficiently than the Bcl-2 homology regions, suggesting that Bcl-rambo may be important other pro-apoptotic pathways.

Gene Name: BCL2-like 13 (apoptosis facilitator)
Family/Subfamily: Apoptosis
Synonyms: BCL2L13, BCL-RAMBO, Bcl-2-like protein 13, Protein Mil1, Bcl2-L-13, MIL1
Target Sequences: NM_015367 NP_056182.2 Q9BXK5

☰ Filters
Antibodies (25)
Proteins (4)
Over-Expression Lysate (2)
Primary (25)
Recombinant (2)
BCL2L13 / Bcl Rambo (29)
Human (25)
Mouse (1)
Rat (1)
Chimpanzee (3)
IHC (5)
IHC-P (2)
WB (23)
ELISA (15)
ICC (1)
IF (4)
IP (2)
Peptide-ELISA (1)
rabbit (18)
mouse (7)
Product Group
IHCPlus (1)
IgG (11)
IgG1 (1)
IgG2a,k (6)
monoclonal mc (7)
polyclonal pc (18)
APC Conjugated (2)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (12)
aa342-369 (6)
aa395-444 (4)
aa1-300 (1)
aa197-225 (1)
No (29)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
BCL2L13 / Bcl Rambo Antibody - Anti-BCL2L13 / Bcl Rambo antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
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BCL2L13 / Bcl Rambo Mouse anti-Human Monoclonal Antibody
Human
ICC, IP, WB
Unconjugated
100 µg/$521
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BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
BCL2L13 / Bcl Rambo Antibody - Immunofluorescence analysis of HeLa cells.
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BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
BCL2L13 / Bcl Rambo Antibody - Immunohistochemistry of paraffin-embedded human heart using antibody at 1:100 dilution.
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BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal (aa1-300) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
BCL2L13 / Bcl Rambo Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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BCL2L13 / Bcl Rambo Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
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BCL2L13 / Bcl Rambo Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
Select
BCL2L13 / Bcl Rambo Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
Select
BCL2L13 / Bcl Rambo Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
Select
BCL2L13 / Bcl Rambo Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
Select
BCL2L13 / Bcl Rambo Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
Select
BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
Select
BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal (aa342-369) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
200 µl/$952
Select
BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal (aa342-369) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal (aa342-369) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal (aa342-369) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal (aa342-369) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
BCL2L13 / Bcl Rambo Antibody - Immunofluorescence analysis of HeLa cells using BCL2L13 Polyclonal Antibody.
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BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
BCL2L13 / Bcl Rambo Antibody - Western blot of anti-BCL2L13 Antibody in CEM cell line lysates (35 ug/lane). BCL2L13(arrow) was detected using the purified antibody.
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BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal (aa197-225) Antibody
Human
WB
Unconjugated
400 µl/$393
BCL2L13 / Bcl Rambo Antibody - Western blot of anti-BCL2L13 Antibody in HeLa cell line lysates (35 ug/lane). BCL2L13(arrow) was detected using the purified antibody.
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BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal (aa342-369) Antibody
Human
WB
Unconjugated
400 µl/$393
BCL2L13 / Bcl Rambo Antibody - BCL2L13 / Bcl Rambo antibody Western blot of H226 Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal (aa395-444) Antibody
Human
WB
Unconjugated
100 µl/$424
BCL2L13 / Bcl Rambo Antibody - BCL2L13 / Bcl Rambo antibody Western blot of H226 Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal (aa395-444) (HRP) Antibody
Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
BCL2L13 / Bcl Rambo Antibody - BCL2L13 / Bcl Rambo antibody Western blot of H226 Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal (aa395-444) (Biotin) Antibody
Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
BCL2L13 / Bcl Rambo Antibody - BCL2L13 / Bcl Rambo antibody Western blot of H226 Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
BCL2L13 / Bcl Rambo Rabbit anti-Human Polyclonal (aa395-444) (FITC) Antibody
Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
Viewing 1-25 of 29 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).