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BCL2L11 / BIM

BCL2-like 11 (apoptosis facilitator)

BCL2L11 / BIM belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.

Gene Name: BCL2-like 11 (apoptosis facilitator)
Family/Subfamily: Apoptosis
Synonyms: BCL2L11, BIM-alpha6, BIM-beta7, Bcl-2-like protein 11, BIM-beta6, BimL, BimS, Bcl-2 interacting protein Bim, BimEL, BAM, Bcl2-L-11, BIM, BOD
Target Sequences: NM_006538 O43521 O43521

☰ Filters
Antibodies (103)
Proteins (12)
ELISA Kits (10)
Cell-Based (1)
Over-Expression Lysate (2)
Primary (103)
Recombinant (10)
Sandwich (8)
Sandwich CLIA (1)
BCL2L11 / BIM (125)
Human (108)
Mouse (56)
Rat (55)
Bovine (2)
Chicken (1)
Dog (4)
Horse (1)
Monkey (9)
Pig (1)
Porcine (1)
Rabbit (2)
Sheep (2)
IHC (51)
IHC-P (11)
WB (87)
Flo (12)
ELISA (39)
ICC (22)
IF (10)
IP (7)
Peptide-ELISA (4)
rabbit (87)
mouse (10)
goat (2)
rat (4)
Product Group
IHCPlus (2)
IgG (47)
IgG1 (4)
IgG1,k (6)
IgG2a (1)
IgG2a,k (2)
IgG2b (1)
monoclonal mc (16)
polyclonal pc (87)
10B12 (1)
1C2C8 (1)
1C2H4 (1)
3C5 (1)
OTI2H5 (2)
12 x 8-Well Microstrips (1)
96-Well Microplate (2)
96-Well Strip Plate (7)
AP Conjugated (2)
APC (1)
APC Conjugated (6)
Atto 390 Conjugated (2)
Atto 488 Conjugated (2)
Atto 594 Conjugated (2)
Azide-free (2)
Biotin Conjugated (10)
Carrier-free (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (8)
HRP Conjugated (6)
PE Conjugated (5)
PerCP Conjugated (2)
Preservative Free (6)
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Unconjugated (54)
Internal (20)
aa2-120 (8)
aa130-165 (7)
aa134-160 (7)
aa22-40 (3)
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aa1-198 (2)
aa20-40 (2)
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1-80 aa (1)
1-80 aa, N-terminal (1)
Ala2 (1)
C-Terminus (1)
Ser69 (1)
aa1-100 (1)
aa1-50 (1)
aa159-169 (1)
pSer69 (1)
pSer69/65 (1)
No (125)
Adherent Cell Cultures (1)
Cell Lysates (1)
Plasma (3)
Serum (3)
Tissue Homogenates (2)
6His, N-terminus (2)
GST (2)
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Human (10)
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293T Cells (1)
E. coli (6)
HEK 293 Cells (1)
Wheat Germ Extract (3)
Yeast (1)
Purified (4)
Low endotoxin level (2)
Select
BCL2L11 / BIM Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
ELISA, Flo, IF, IP, WB
Unconjugated
100 µl/$688
BCL2L11 / BIM Antibody - Anti-BCL2L11 / BIM antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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BCL2L11 / BIM Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
BCL2L11 / BIM Antibody - Anti-BCL2L11 / BIM antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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BCL2L11 / BIM Rabbit anti-Human Polyclonal (aa134-160) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$460
BCL2L11 / BIM ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$902
BCL2L11 / BIM Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using BIM Antibody. The picture on the right is blocked with the synthesized peptide.
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BCL2L11 / BIM Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
BCL2L11 / BIM Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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BCL2L11 / BIM Mouse anti-Human Monoclonal (1C2C8) Antibody
Mouse, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$412
Select
BCL2L11 / BIM Rabbit anti-Human Monoclonal (Preservative Free) (Biotin) Antibody
Human
ELISA, IP, WB
Biotin Conjugated, Preservative Free
50 µg/$343
Select
BCL2L11 / BIM Rabbit anti-Human Monoclonal (Preservative Free) Antibody
Human
ELISA, IP, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
BCL2L11 / BIM Antibody - Immunohistochemical analysis of BIM (pS69) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX. w
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BCL2L11 / BIM Rabbit anti-Human Polyclonal (pSer69) Antibody
Mouse, Sheep, Bovine, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$315
BCL2L11 / BIM Antibody - Immunohistochemistry of Bim in human skin cancer cells with Bim antibody at 20 µg/ml.
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BCL2L11 / BIM Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
BCL2L11 / BIM Protein
Select
E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261; 20 µg/$298; 100 µg/$454; 500 µg/$1,177
Select
BCL2L11 / BIM Rabbit anti-Human Polyclonal (aa134-160) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
Select
BCL2L11 / BIM Rabbit anti-Human Polyclonal (pSer59) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
BCL2L11 / BIM Antibody - Western blot analysis of Bim in K562 (Left) and A549 (Right) whole cell lysates using a 1:1000 dilution of BCL2L11 / BIM antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BCL2L11 / BIM Rabbit anti-Human Polyclonal (Internal) (Biotin) Antibody
Mouse, Rat, Human
IHC, WB
Biotin Conjugated
100 µg/$447
Select
BCL2L11 / BIM Rabbit anti-Human Polyclonal (Preservative Free) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50 µg/$343
BCL2L11 / BIM Antibody - Antibody staining (0.5 ug/ml) of K562lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
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BCL2L11 / BIM Goat anti-Human Polyclonal (aa159-169) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
Select
BCL2L11 / BIM Mouse anti-Human Monoclonal (aa1-100) Antibody
Human
ELISA
Unconjugated
100 µg/$705
Select
BCL2L11 / BIM Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
100 µl/$904
BCL2L11 / BIM Antibody - A) Western blot using anti-Bim, mAb (10B12) detecting EE mouse BimS, BimL, BimEL and EE human, BimSS, BimS, BimLS, BimL, BimELS, BimEL. Probing with an anti-Hsp-70 mAb was used as a loading control for all blots. B) Western blot using anti-Bim, mAb (10B12) detecting endogenous Bim expression in mouse tissues but not in Bim knockout mice. Bim protein was revealed in lysates from mouse tissues (5 x 106/lane) and detection by ECL. Probing with an anti-Hsp-70 mAb was used as a loading control.
Select
BCL2L11 / BIM Rat anti-Mouse Monoclonal (aa20-40) (10B12) Antibody
Mouse, Dog, Rat, Human, Monkey
ELISA, Flo, ICC, IHC, IP, WB
Unconjugated
100 µg/$435
BCL2L11 / BIM Antibody - A) Western blot using anti-Bim, mAb (3C5) detecting EE mouse BimS, BimL, BimEL and EE human, BimSS, BimS, BimLS, BimL, BimELS, BimEL. Probing with an anti-Hsp-70 mAb was used as a loading control for all blots. B) Western blot using anti-Bim, mAb (3C5) detecting endogenous Bim expression in mouse tissues but not in Bim knockout mice. Bim protein was revealed in lysates from mouse tissues (5 x 106/lane) and detection by ECL. Probing with an anti-Hsp-70 mAb was used as a loading control.
Select
BCL2L11 / BIM Rat anti-Mouse Monoclonal (aa20-40) (3C5) Antibody
Mouse, Dog, Rat, Human, Monkey
ELISA, Flo, ICC, IHC, IP, WB
Unconjugated
100 µg/$435
BCL2L11 / BIM Antibody - Immunohistochemistry analysis of human testis tissue at a dilution of 1:100
Select
BCL2L11 / BIM Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
Select
BCL2L11 / BIM Rat anti-Mouse Monoclonal Antibody
Mouse, Human, Monkey
Flo, ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$763
Select
BCL2L11 / BIM Rat anti-Mouse Monoclonal Antibody
Mouse, Human, Monkey
Flo, ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$866
BCL2L11 / BIM Antibody - Immunocytochemistry of BIM EL inK562 cells with BIM EL antibody at 2.5 ug/ml.
Select
BCL2L11 / BIM Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, WB
Unconjugated
0.1 mg/$460
Select
BCL2L11 / BIM Mouse anti-Human Monoclonal (1C2H4) Antibody
Mouse, Rat, Human
ELISA, ICC, IF, WB
Unconjugated
0.1 mg/$502
Viewing 1-25 of 125 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).