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Anti-BCL2L1 / BCL-XL Antibody (Ser62) IHC-plus™ LS-B1175

Note: This antibody replaces LS-C34297, LS-C74749, LS-C51197, LS-C118064

Ordering

Wt. Vol. Conc. Price
50 µg - - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular BCL2L1 / BCL-XL Antibodies

Anti-BCL2L1 / BCL-XL Antibody (aa46-66) LS-C12146
Rabbit Polyclonal (IgG) to Human BCL2L1 / BCL-XL
Human, Mouse, Rat, Dog, Hamster, Pig
IHC - Paraffin, Western blot
Unconjugated
Anti-BCL2L1 / BCL-XL Antibody (Internal) LS-C141890
Rabbit Polyclonal to Human BCL2L1 / BCL-XL
Human, Mouse, Rat, Cat, Dog, Hamster, Pig, Rabbit, Sheep
Western blot
Unconjugated
Western blot Image

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Rabbit Polyclonal (IgG) to Human BCL2L1 / BCL-XL
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated

Details

Human BCL2L1 / BCL-XL
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • Western blot

Specificity and Use

BCL2L1 / BCL-XL antibody was raised against synthetic peptide from human BCL2L1 / Bcl-xL.
Ser62
Amino acids surrounding Serine 62 of human BCL2L1
Immunohistochemistry: LS-B1175 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1175 was determined to be 10 ug/ml.

Packaging

PBS, 0.02% sodium azide, 50% glycerol.
Long term: -70°C; Short term: -20°C
For research use only.

About BCL2L1 / BCL-XL

Q07817 NM_001191 NP_001182.1

BCL2L1 Antibody, Apoptosis regulator Bcl-X Antibody, Bcl-xL Antibody, BCL-XL/S Antibody, BCLXS Antibody, Bcl-2-like protein 1 Antibody, BCL2-like 1 Antibody, BCL2L Antibody, Bcl-X Antibody, Bcl-xS Antibody, BCLXL Antibody, PPP1R52 Antibody, Bcl2-L-1 Antibody, BCLX Antibody

Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane.

Immunohistochemistry

Immunohistochemistry
Anti-BCL2L1 / Bcl-x antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1175 concentration 10 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-BCL2L1 / Bcl-x antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1175 concentration 10 ug/ml.

Western blot

Western blot
Western blot of extracts from 293 and HeLa cells using BCL-XL(Ab-62) antibody.
 

Requested From: United States
Date Requested: 12/7/2016

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