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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BCL2L1 / BCL‑XL Antibody (N‑Terminus) LS‑C112277
BCL-XL antibody LS-C112277 is an unconjugated rabbit polyclonal antibody to BCL-XL (BCL2L1) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C112277-50
50 µg
Unavailable

Popular BCL2L1 / BCL-XL Products

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Species: Human, Mouse, Rat, Dog, Hamster, Pig
Applications: IHC, IHC - Paraffin, Western blot
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Detection of Bcl-x in A431 whole cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Applications: Western blot
Western blot Image
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit
Applications: Western blot

Product Description

BCL-XL antibody LS-C112277 is an unconjugated rabbit polyclonal antibody to BCL-XL (BCL2L1) from human, mouse, rat and other species. Validated for WB.
About BCL2L1 / BCL-XL
Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Q07817 NM_001191 NP_001182.1

BCL2L1 Antibody, Apoptosis regulator Bcl-X Antibody, Bcl-xL Antibody, BCL-XL/S Antibody, BCLXS Antibody, Bcl-2-like protein 1 Antibody, BCL2-like 1 Antibody, BCL2L Antibody, Bcl-X Antibody, Bcl-xS Antibody, BCLXL Antibody, PPP1R52 Antibody, Bcl2-L-1 Antibody, BCLX Antibody


Specifications

Target
Human BCL2L1 / BCL-XL
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Sheep (tested or 100% immunogen sequence identity)
Predicted
Guinea pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
BCL2L1 / BCL-XL antibody was raised against synthetic peptide from N-Terminus of human BCL2L1 (Q07817, NP_612815). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Sheep, Hamster, Elephant, Panda, Dog, Cat, Bovine, Bat, Rabbit, Horse, Pig (100%); Galago, Guinea pig (91%); Opossum (83%).
Blocking Peptide
LS-E10543 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C112277. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
Human BCL2L1 / Bcl-xL
Usage
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Presentation
Lyophilized
Reconstitution
Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

BCL2L1 / Bcl-x antibody LS-C112277 Western blot of Fetal Thymus lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
BCL2L1 / Bcl-x antibody LS-C112277 Western blot of Fetal Thymus lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

BCL2L1 / Bcl-x antibody LS-C112277 Western blot of Fetal Thymus lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
BCL2L1 / Bcl-x antibody LS-C112277 Western blot of Fetal Thymus lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

BCL2L1 / Bcl-x antibody LS-C112277 Western blot of Fetal Thymus lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
BCL2L1 / Bcl-x antibody LS-C112277 Western blot of Fetal Thymus lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

BCL2L1 / Bcl-x antibody LS-C112277 Western blot of Fetal Thymus lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
BCL2L1 / Bcl-x antibody LS-C112277 Western blot of Fetal Thymus lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/20/2018

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