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BCL2L1 / BCL-XL
BCL2-like 1
Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F1F0 activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles.Isoform Bcl-X(S) promotes apoptosis.
| Gene Name: | BCL2-like 1 |
| Family/Subfamily: | Apoptosis |
| Synonyms: | BCL2L1, Apoptosis regulator Bcl-X, Bcl-xL, BCL-XL/S, BCLXS, Bcl-2-like protein 1, BCL2-like 1, BCL2L, Bcl-X, Bcl-xS, BCLXL, PPP1R52, Bcl2-L-1, BCLX |
| Target Sequences: | NM_001191 NP_001182.1 Q07817 |
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BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (OTI2D1) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (aa1-208) Antibody
Mouse, Rat, Human
ICC, IF, IHC-P, IP, WB
Unconjugated
50 µl/$460
BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (BX006) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Hamster, Pig, Horse, Chimpanzee, Human, Monkey
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
20 µg/$371; 100 µg/$574
BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (Ready-to-Use) (BX006) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Hamster, Pig, Horse, Chimpanzee, Human, Monkey
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Ready-to-Use
7 ml/$574
BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (Azide-free, BSA-free) (BX006) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Hamster, Pig, Horse, Chimpanzee, Human, Monkey
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (pSer62) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$315
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$564
BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (aa3-14) (Azide-free, BSA-free) (SPM165) Antibody
Rabbit, Mouse, Dog, Sheep, Bovine, Rat, Hamster, Pig, Horse, Bat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (aa46-66) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Gerbil, Human
IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µl/$460
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (pThr47) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (Biotin) (7B2.5) Antibody
Human
Flo, IHC, IP, WB
Biotin Conjugated
0.1 mg/$479
BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (PE) Antibody
Human
Flo, IHC, IP, WB
PE Conjugated
100 µg/$665
BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (aa1-209) (2C11C2) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$316; 100 µg/$386
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (pSer62) Antibody
IF, IHC, WB
Unconjugated
50 µl/$341; 100 µl/$431; 200 µl/$539
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (aa46-66) Antibody
Mouse, Dog, Rat, Hamster, Pig, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$498
BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (2H12) Antibody
Mouse, Human
IP, WB
Unconjugated
25 µg/$276; 100 µg/$352
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (aa1-209) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (pThr47) Antibody
Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$315
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (pThr47) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (804CT19.1.4) Antibody
Mouse, Rat, Human
WB
Unconjugated
400 µl/$393
BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (aa3-14) (Azide-free, BSA-free) (SPM337) Antibody
Rabbit, Mouse, Dog, Sheep, Bovine, Rat, Hamster, Pig, Horse, Bat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
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