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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BCL2L1 / BCL‑XL Antibody (clone 2D1) LS‑C174729
BCL-XL antibody LS-C174729 is an unconjugated mouse monoclonal antibody to human BCL-XL (BCL2L1). Validated for IHC and WB.
Catalog
Size
Price
LS-C174729-100
100 µl (1 mg/ml)
Unavailable

Popular BCL2L1 / BCL-XL Products

Antibody
Species: Human, Mouse, Rat, Dog, Hamster, Pig
Applications: IHC, IHC - Paraffin, Western blot
Anti-BCL2L1 / Bcl-x antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1175 concentration 10 ug/ml.
Species: Human, Mouse, Rat
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Antibody
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Detection of Bcl-x in A431 whole cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat, Cat, Dog, Hamster, Pig, Rabbit, Sheep
Applications: Western blot
Western blot Image
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit
Applications: Western blot

Product Description

BCL-XL antibody LS-C174729 is an unconjugated mouse monoclonal antibody to human BCL-XL (BCL2L1). Validated for IHC and WB.
About BCL2L1 / BCL-XL
Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Q07817 NM_001191 NP_001182.1

BCL2L1 Antibody, Apoptosis regulator Bcl-X Antibody, Bcl-xL Antibody, BCL-XL/S Antibody, BCLXS Antibody, Bcl-2-like protein 1 Antibody, BCL2-like 1 Antibody, BCL2L Antibody, Bcl-X Antibody, Bcl-xS Antibody, BCLXL Antibody, PPP1R52 Antibody, Bcl2-L-1 Antibody, BCLX Antibody


Specifications

Target
Human BCL2L1 / BCL-XL
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [2D1]
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:150)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
BCL2L1 / BCL-XL antibody was raised against full length human recombinant protein of human BCL2L1(NP_612815) produced in HEK293T cell.
Specificity
Human bcl-xl
Presentation
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of paraffin-embedded Human bladder tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Human bladder tissue using anti-BCL2L1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-BCL2L1 mouse monoclonal antibody.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL2L1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL2L1.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL2L1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL2L1.

Immunohistochemistry

IHC of paraffin-embedded Human bladder tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Human bladder tissue using anti-BCL2L1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-BCL2L1 mouse monoclonal antibody.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL2L1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL2L1.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL2L1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL2L1.

Immunohistochemistry

IHC of paraffin-embedded Human bladder tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Human bladder tissue using anti-BCL2L1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-BCL2L1 mouse monoclonal antibody.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL2L1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL2L1.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL2L1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL2L1.

Immunohistochemistry

IHC of paraffin-embedded Human bladder tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Human bladder tissue using anti-BCL2L1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-BCL2L1 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-BCL2L1 mouse monoclonal antibody.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL2L1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL2L1.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL2L1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL2L1.


Requested From: 
Date Requested: 6/22/2018

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